HISTOCHEMICAL-STUDY OF ALKALINE-PHOSPHATASE IN PRIMARY HUMAN BRAIN-TUMORS - DIAGNOSTIC IMPLICATIONS FOR MENINGIOMAS AND NEURINOMAS

被引：6
|
作者：
MURAKAMI, M [1 ]
KURATSU, JI [1 ]
MIHARA, Y [1 ]
MATSUNO, K [1 ]
USHIO, Y [1 ]
KEPES, JJ [1 ]
机构：
[1] KUMAMOTO UNIV,SCH MED,DEPT ANAT 2,KUMAMOTO 860,JAPAN
来源：
NEUROSURGERY | 1993年 / 32卷 / 02期
关键词：
ALKALINE PHOSPHATASE; BRAIN TUMOR; HISTOCHEMISTRY; HUMAN;
D O I：
10.1227/00006123-199302000-00005
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
HISTOCHEMICAL ANALYSIS OF frozen, thin sections revealed the distribution of alkaline phosphatase (ALPase) in 47 primary intracranial neoplasms in humans. The cytoplasm of meningioma cells exhibited the strongest ALPase reactivity. Pretreatment of these materials by levamisol indicated that the isozymes of ALPase had the characteristic liver-bone-kidney form. In meningiomas and astrocytomas, there was no particular relationship between ALPase activity and malignancy. In neurinomas, there was weak ALPase reactivity in a few neoplastic cells. These findings are suggestive of diagnostic implications for fibroblastic meningiomas and neurinomas at the light microscopic level.
引用
收藏
页码：180 / 184
页数：5
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