DETECTION OF THE ILLEGAL USE OF ETHINYLESTRADIOL IN CATTLE URINE BY GAS-CHROMATOGRAPHY MASS-SPECTROMETRY

被引：14
作者：
DAESELEIRE, E
DEGUESQUIERE, A
VANPETEGHEM, C
机构：
[1] Laboratory of Food Analysis, Faculty of Pharmaceutical Sciences, State University of Ghent, B-9000 Ghent
来源：
JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS | 1991年 / 564卷 / 02期
关键词：
D O I：
10.1016/0378-4347(91)80515-E
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A method for the detection of ethinylestradiol in cattle urine is described, based on enzymic hydrolysis of the sample, clean-up by means of disposable octadecyl and amino solid-phase extraction columns, fractionation by reversed-phase high-performance liquid chromatography, and detection by gas chromatography-mass spectrometry (selected-ion monitoring). Identification is based on both gas chromatographic and mass spectrometric data. The method has been tested on urine samples for a collaborative study and all the results found were correct.
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页码：469 / 475
页数：7
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