SEVERITY AND FREQUENCY OF MITRAL REGURGITATION IN PATIENTS PRESENTING WITH ACUTE MYOCARDIAL INFARCTION

Objectives: Methodology: Results: Conclusion: The aim of our study was to determine the frequency and severity of MR in patients presenting with STEMI after emergency reperfusion treatment with primary percutaneous coronary Intervention (P-PCI) or streptokinase (SK) during hospital stay. Methodology: This cross-sectional study was conducted at National Institute of Cardiovascular Diseases (NICVD), Karachi for six month of duration from 1st August 2013 to 31st January 2014. Patients of both genders aged between 2060 years presenting with STEMI who underwent emergency reperfusion therapy with primary percutaneous coronary Intervention (P-PCI) or streptokinase (SK) were included in the study. Descriptive analyses were performed for socieo-demographic characteristics while Chi-square test was applied for the association of different characteristics among various categories of mitral regurgitation. Results: Total of 262 patients were included in the study with mean age of 53.9 +/- 7.1 years. Of them 68% of the patients were males. Mitral regurgitation (mild, moderated and severe) with different characteristics was found in 58% (152) patients. Elderly patients with acute inferior wall MI (IWMI) and those receiving SK were more likely to have MR. Furthermore patients with IWMI and those receiving SK were more likely to suffer from severe grade ofMR(p <= 0.05). Conclusion: MR is a frequent complication of STEMI and it was more frequent in patients with IWMI or who received SK as a mean of emergency thrombolysis.