NOSOCOMIAL SPREAD OF HEPATITIS-B VIRUS (HBV) IN A HEMODIALYSIS UNIT CONFIRMED BY HBV DNA-SEQUENCING

被引：30

作者：

ROLL, M

NORDER, H

MAGNIUS, LO

GRILLNER, L

LINDGREN, V

机构：

[1] DANDERYD HOSP,DEPT BACTERIOL & HOSP INFECT CONTROL,S-18288 DANDERYD,SWEDEN

[2] DANDERYD HOSP,DEPT MED,NEPHROL SECT,S-18288 DANDERYD,SWEDEN

[3] SWEDISH INST INFECT DIS CONTROL,S-10521 STOCKHOLM,SWEDEN

[4] KAROLINSKA HOSP,DEPT CLIN MICROBIOL,S-17176 STOCKHOLM,SWEDEN

来源：

JOURNAL OF HOSPITAL INFECTION | 1995年 / 30卷 / 01期

关键词：

OUTBREAK; HEPATITIS B VIRUS; HEMODIALYSIS UNIT; DNA SEQUENCE ANALYSIS; TRANSMISSION; VACCINATION;

D O I：

10.1016/0195-6701(95)90249-X

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

An outbreak of hepatitis B virus (HBV) infection in a haemodialysis unit is described. Four patients in the unit contracted subclinical HBV infection within three months. DNA sequence analysis of the S gene of HBV isolates from chronic carriers and newly infected patients in the unit aided in tracing possible transmission pathways. Three newly infected patients had received partial or complete HBV vaccination previously. HBV was rapidly cleared from all three although the anti-HBs titre had not reached 10 IU L(-1) in any of them at the time of infection.

引用

页码：57 / 63

页数：7

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