INTERLEUKIN-10 IN THE VITREOUS OF PATIENTS WITH PRIMARY INTRAOCULAR LYMPHOMA

被引：132
作者：
CHAN, CC
WHITCUP, SM
SOLOMON, D
NUSSENBLATT, RB
机构：
[1] NEI,CLIN BRANCH,BETHESDA,MD 20892
[2] NCI,PATHOL LAB,CYTOPATHOL SECT,BETHESDA,MD
来源：
AMERICAN JOURNAL OF OPHTHALMOLOGY | 1995年 / 120卷 / 05期
关键词：
D O I：
10.1016/S0002-9394(14)72217-2
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
PURPOSE: To find an accurate and simple method to diagnose primary intraocular lymphoma. METHODS: We prospectively analyzed concentrations of interleukin-10, interleukin-1, interleukin-2, interleukin-4, and interleukin-6 in vitrectomy specimens from three patients with primary intraocular lymphoma and five patients with uveitis by enzyme-linked immunosorbent assay. RESULTS: Interleukin-10 in the vitreous was detected in patients with primary intraocular lymphoma. Interleukin-10 levels correlated with clinical activity and the number of malignant cells. CONCLUSION: Concentrations of interleukin-10 in the vitreous may be a helpful clue to both clinicians and pathologists in diagnosing primary intraocular lymphoma.
引用
收藏
页码：671 / 673
页数：3
相关论文
共 5 条
  • [1] BLAY JY, 1993, BLOOD, V82, P2169
  • [2] FREEMAN LN, 1987, OPHTHALMOLOGY, V94, P1631
  • [3] PRIMARY CENTRAL NERVOUS-SYSTEM LYMPHOMA
    HOCHBERG, FH
    MILLER, DC
    [J]. JOURNAL OF NEUROSURGERY, 1988, 68 (06) : 835 - 853
  • [4] INTERLEUKIN-10 IS A POTENT GROWTH AND DIFFERENTIATION FACTOR FOR ACTIVATED HUMAN LYMPHOCYTES-B
    ROUSSET, F
    GARCIA, E
    DEFRANCE, T
    PERONNE, C
    VEZZIO, N
    HSU, DH
    KASTELEIN, R
    MOORE, KW
    BANCHEREAU, J
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (05) : 1890 - 1893
  • [5] WHITCUP SM, 1993, OPHTHALMOLOGY, V100, P1399
1