INTERLEUKIN-10 IN THE VITREOUS OF PATIENTS WITH PRIMARY INTRAOCULAR LYMPHOMA

被引：132

作者：

CHAN, CC

WHITCUP, SM

SOLOMON, D

NUSSENBLATT, RB

机构：

[1] NEI,CLIN BRANCH,BETHESDA,MD 20892

[2] NCI,PATHOL LAB,CYTOPATHOL SECT,BETHESDA,MD

来源：

AMERICAN JOURNAL OF OPHTHALMOLOGY | 1995年 / 120卷 / 05期

关键词：

D O I：

10.1016/S0002-9394(14)72217-2

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

PURPOSE: To find an accurate and simple method to diagnose primary intraocular lymphoma. METHODS: We prospectively analyzed concentrations of interleukin-10, interleukin-1, interleukin-2, interleukin-4, and interleukin-6 in vitrectomy specimens from three patients with primary intraocular lymphoma and five patients with uveitis by enzyme-linked immunosorbent assay. RESULTS: Interleukin-10 in the vitreous was detected in patients with primary intraocular lymphoma. Interleukin-10 levels correlated with clinical activity and the number of malignant cells. CONCLUSION: Concentrations of interleukin-10 in the vitreous may be a helpful clue to both clinicians and pathologists in diagnosing primary intraocular lymphoma.

引用

页码：671 / 673

页数：3

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