The role of genetic, autoimmune, infective and hormonal factors in pathogenesis of lichen sclerosus - review of the literature

被引：0

作者：

Cegielska, Agnieszka

Imko-Walczuk, Beata ^{[1
,2
]}

Jaskiewicz, Janusz ^{[3
]}

Placek, Waldemar ^{[4
]}

机构：

[1] Pomorskiego Ctr Traumatol Gdansku, Oddzial Dermatol, Gdansk, Poland

[2] Wyzsza Szkola Zawodowa Pielegnacji Zdrowia & Urod, Poznan, Poland

[3] Gdanskiego Uniwersytetu Med, Katedra & Klin Chirurg Onkol, Gdansk, Poland

[4] Uniwersytetu Mikolaja Kopernika Toruniu, Coll Med Bydgoszczy, Katedra & Klin Dermatol Chorob Przenoszonych Drog, Torun, Poland

来源：

PRZEGLAD DERMATOLOGICZNY | 2011年 / 98卷 / 04期

关键词：

lichen sclerosus at atrophicus; lichen sclerosus; etiopathogenesis; HLA; ECM1; hormons; oxidative stress;

D O I：

暂无

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Lichen sclerosus (LS) is a chronic inflammatory disease with a characteristic clinical appearance and specific histopathology. Clinically is characterized by plaques of ivory white atrophic lesions licalized, chiefly on genitals, and also in extragenital localisation. Both males and females at any age are affected. The aetiology of LS remains unclear. In the literature, the hypothesis of possible role of genetic, autoimmune, infectious and hormonal factors are found. Oxidative stress may also play additional role. Understanding of lichen sclerosus pathogenesis may improve its therapy and allow to avoid its complications.

引用

页码：355 / 361

页数：7

共 28 条

[11] Genital verrucous carcinoma is associated with lichen sclerosus: a retrospective study and review of the literature
Wang, S-H
Chi, C-C
Wong, Y. W.
Salim, A.
Manek, S.
Wojnarowska, F.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2010, 24 (07) : 815 - 819
[12] The Surgical Management of Lichen Sclerosus of the Glans Penis: Our Experience and Review of the Literature
Garaffa, Giulio
Shabbir, Majid
Christopher, Nim
Minhas, Suks
Ralph, David J.
JOURNAL OF SEXUAL MEDICINE, 2011, 8 (04) : 1246 - 1253
[13] Does lichen sclerosus play a central role in the pathogenesis of human papillomavirus negative vulvar squamous cell carcinoma? The itch-scratch-lichen sclerosus hypothesis
Scurry, J
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 1999, 9 (02) : 89 - 97
[14] Genital Vulvar Lichen Sclerosus in Monozygotic Twin Women: A Case Report and Review of the Literature
Doulaveri, Georgeta
Armira, Kalliopi
Kouris, Anargyros
Karypidis, Dimitrios
Potouridou, Irene
CASE REPORTS IN DERMATOLOGY, 2013, 5 (03): : 321 - 325
[15] Lichen sclerosus of the oral mucosa: clinical and histopathological findings. Review of the literature and a case report
Matela, Anna-Maija
Hagstrom, Jaana
Ruokonen, Hellevi
ACTA ODONTOLOGICA SCANDINAVICA, 2018, 76 (05) : 364 - 373
[16] Genital lichen sclerosus developing around 'ectopic' urethral orifices supports the role of occlusion and urine in its pathogenesis
Gupta, Vishal
Gupta, Somesh
INTERNATIONAL JOURNAL OF STD & AIDS, 2017, 28 (09) : 940 - 942
[17] A Rare Presentation of Lichen Sclerosus Involving the Vaginal Canal After Radiation Therapy: A Case Report and Review of the Literature
Brandon, Arcole
Joshi, Tanvi
Ahmed, Zan
Tahir, Muhammad
Phung, Thuy
Pierce, Jennifer Y.
Knowles, Kurt
CUREUS JOURNAL OF MEDICAL SCIENCE, 2023, 15 (10)
[18] Evaluation of the effectiveness of treatment of vulvar lichen sclerosus et atrophicus. Analysis of own material and review of the literature
Gajewska, Malgorzata
Jagodzinska, Aleksandra
Wielgos, Miroslaw
NEUROENDOCRINOLOGY LETTERS, 2018, 39 (05) : 417 - 421
[19] A critical review of the role of endothelial factors in the pathogenesis of hypertension
Schiffrin, EL
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2001, 38 : S3 - S6
[20] Topical 5-aminolevulinic acid (ALA)-photodynamic therapy (PDT) for lichen sclerosus of face: case report and literature review
Tommasino, Nello
Lauletta, Giuseppe
Spano, Gustavo
Scaramuzzino, Lorenzo
Salvatores, Gaia De Fata
Scalvenzi, Massimiliano
Coronella, Luigi
LASERS IN MEDICAL SCIENCE, 2024, 39 (01)

← 1 2 3 →