Cardiorespiratory parameters during submaximal exercise under acute exposure to normobaric and hypobaric hypoxia

被引：27

作者：

Basualto-Alarcon, Carla ^{[1
]}

Rodas, Gil ^{[2
]}

Galilea, Pedro A. ^{[3
]}

Riera, Joan ^{[3
]}

Pages, Teresa ^{[4
]}

Ricart, Antoni ^{[5
]}

Torrella, Joan R. ^{[4
]}

Behn, Claus ^{[1
]}

Viscor, Gines ^{[4
]}

机构：

[1] Univ Chile, Fac Med, Lab Ambientes Extremos ICBM, Santiago, Chile

[2] Futbol Club Barcelona, Med Serv, Barcelona, Spain

[3] Ctr Alt Rendiment Esportiu CAR, GIRSANE, Barcelona, Spain

[4] Univ Barcelona, Dept Fisiol & Immunol, Barcelona, Spain

[5] Hosp Univ Bellvitge, Barcelona, Spain

来源：

APUNTS-MEDICINA DE L ESPORT | 2012年 / 47卷 / 174期

关键词：

Heart rate variability; Hypoxia tolerance; Hypoxic tent; Hypobaric chamber; Arterial oxygen saturation;

D O I：

10.1016/j.apunts.2011.11.005

中图分类号：

G8 [体育];

学科分类号：

04 ; 0403 ;

摘要：

Seven healthy young men were submitted twice to a hypoxia tolerance test at a simulated altitude (3000 m). Their first acute exposure was in a hypobaric chamber; and the second, in a hypoxic tent. Cardiorespiratory parameters and heart rate variability measurements were obtained under each hypoxic condition. A significant decrease of 6% to 8% compared to normal oxygen conditions was observed in arterial oxygen saturation (SpO(2)) in both hypoxic conditions at rest; whereas exercise led to decreases of 10% in SpO(2) despite an increase of 27% in respiratory minute volume. The low frequency (LF) and high frequency (HF) components of heart rate variability significantly changed from normoxia (LF: 37.1, HF: 62.9, LF/HF: 1.27) to hypobaric hypoxia (HH) (LF: 49.1, HF: 50.6, LF/HF: 1.96). However, these changes were not observed under normobaric hypoxia. Thus, heart rate variability behaved differently in the two hypoxic conditions, supporting the hypothesis that normobaric hypoxia and hypobaric hypoxia are not equal stimuli to the cardiovascular and respiratory systems. A correlation was found between sympathetic and vagal modulations in normoxia and SpO2 at exercise under hypobaric hypoxia (HH). Individuals with higher sympathetic modulation (LF%) in normoxia had higher SpO2 at exercise under HH (r = 0.808, P < 0.05) and individuals with higher vagal modulation (HF%) in normoxia showed a trend to lower SpO2 in exercise under HH (r = -0.636, P = 0.125). This opens up the possibility of using this correlation as a tool for predicting the individual capacity to altitude acclimatization. (C) 2011 Consell Catala de l'Esport. Generalitat de Catalunya. Published by Elsevier Espana, S.L. All rights reserved.

引用

页码：65 / 72

页数：8

共 43 条

[1]

Grant S., MacLeod N., Kay J.W., Watt M., Patel S., Paterson A., Et al., Sea level and acute responses to hypoxia: do they predict physiological responses and acute mountain sickness at altitude?, Br J Sports Med, 36, pp. 141-146, (2002)

[2]

Calbet J.A.L., Radegran G., Boushel R., Sondergaard H., Saltin B., Wagner P.D., Effect of blood haemoglobin concentration on V(O2,max) and cardiovascular function in lowlanders acclimatised to 5260m, J Physiol (Lond), 545, pp. 715-728, (2002)

[3]

Basnyat B., Murdoch D.R., High-altitude illness, Lancet, 361, pp. 1967-1974, (2003)

[4]

Calbet J.A.L., Boushel R., Radegran G., Sondergaard H., Wagner P.D., Saltin B., Determinants of maximal oxygen uptake in severe acute hypoxia, Am J Physiol, 284, (2003)

[5]

Calbet J.A.L., Boushel R., Radegran G., Sondergaard H., Wagner P.D., Saltin B., Why is VO2 max after altitude acclimatization still reduced despite normalization of arterial O2 content?, Am J Physiol, 284, (2003)

[6]

Cerretelli P., Limiting factors to oxygen transport on Mount Everest, J Appl Physiol, 40, pp. 658-667, (1976)

[7]

Bernardi L., Passino C., Spadacini G., Calciati A., Robergs R., Greene R., Et al., Cardiovascular autonomic modulation and activity of carotid baroreceptors at altitude, Clin Sci, 95, pp. 565-573, (1998)

[8]

Magalhaes J., Ascensao A., Viscor G., Soares J., Oliveira J., Marques F., Et al., Oxidative stress in humans during and after 4hours of hypoxia at a simulated altitude of 5500m, Aviat Space Environ Med, 75, pp. 16-22, (2004)

[9]

Rapino C., Bianchi G., Giulio C.D., Centurione L., Cacchio M., Antonucci A., Et al., HIF-1α cytoplasmic accumulation is associated with cell death in old rat cerebral cortex exposed to intermittent hypoxia, Aging Cell, 4, pp. 177-185, (2005)

[10]

Sztajzel J., Heart rate variability: a noninvasive electrocardiographic method to measure the autonomic nervous system, Swiss Med Wkly, 134, pp. 514-522, (2004)

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