SYNTHESIS OF FLUORESCEINYL-NEUROKININ-A, A BIOLOGICALLY-ACTIVE PROBE FOR NK2 RECEPTORS

被引：1

作者：

CESZKOWSKI, K

CHOLLET, A

机构：

[1] Glaxo Institute for Molecular Biology S.A., CH-1228 Plan-les-Ouates

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1992年 / 2卷 / 06期

关键词：

D O I：

10.1016/S0960-894X(01)81208-7

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The tachykinin peptide neurokinin-A has been selectively labelled at a single site with fluorescein isothiocyanate. The fluorescein-labelled neurokinin-A (F-NKA) retained full binding affinity for the NK2 receptor as well as functional activity. F-NKA was used as a tool to study NK2 receptor in cell lines by flow cytometry.

引用

页码：609 / 612

页数：4

共 7 条

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