Can propolis and caffeic acid phenethyl ester be promising agents against cyclophosphamide toxicity?

被引:10
|
作者
Akyol, Sumeyya [1 ]
Gulec, Mehmet Akif [2 ]
Erdemli, Haci Kemal [3 ]
Akyol, Omer [4 ]
机构
[1] Turgut Ozal Univ, Fac Med, Dept Med Biol, Ankara, Turkey
[2] Turgut Ozal Univ, Fac Med, Dept Med Biochem, Ankara, Turkey
[3] Corum Training & Res Hosp, Dept Biochem Lab, Corum, Turkey
[4] Hacettepe Univ, Fac Med, Dept Med Biochem, TR-06100 Ankara, Turkey
来源
关键词
Caffeic acid phenethyl ester; cyclophosphamide; propolis;
D O I
10.5455/jice.20160127024542
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Propolis is a mixture having hundreds of polyphenols including caffeic acid phenethyl ester (CAPE). They have been using in several medical conditions/diseases in both in vitro and in vivo experimental setup. Cyclophosphamide (CP) has been used to treat a broad of malignancies including Hodgkin's and non-Hodgkin's lymphoma, Burkitt's lymphoma, chronic lymphocytic leukemia, Ewing's sarcoma, breast cancer, testicular cancer, etc. It may cause several side effects after treatment. In this mini review, the protective effects of propolis and CAPE were compared each other in terms of effectiveness against CP-induced injuries.
引用
收藏
页码:105 / 107
页数:3
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