EPIDEMIOLOGY OF MULTIPLE-SCLEROSIS IN ARABS IN KUWAIT - A COMPARATIVE-STUDY BETWEEN KUWAITIS AND PALESTINIANS

被引：73

作者：

ALDIN, ASN

KHOGALI, M

POSER, CM

ALNASSAR, KE

SHAKIR, R

HUSSAIN, J

BEHBAHANI, K

CHADHA, G

机构：

[1] HARVARD UNIV,SCH MED,DEPT NEUROL,NEUROL UNIT,330 BROOKLINE AVE,BOSTON,MA 02215

[2] KUWAIT UNIV,FAC MED,DEPT MED,KUWAIT,KUWAIT

[3] KUWAIT UNIV,FAC MED,DEPT BIOCHEM,KUWAIT,KUWAIT

[4] KUWAIT UNIV,FAC MED,DEPT MICROBIOL,KUWAIT,KUWAIT

[5] KUWAIT UNIV,FAC MED,DEPT COMMUNITY MED,KUWAIT,KUWAIT

来源：

JOURNAL OF THE NEUROLOGICAL SCIENCES | 1990年 / 100卷 / 1-2期

关键词：

MULTIPLE SCLEROSIS; EPIDEMIOLOGY; COMPARATIVE STUDY; ARABS;

D O I：

10.1016/0022-510X(90)90024-H

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

On December 31, 1988 there were 201 registered multiple sclerosis patients in Kuwait, an overall prevalence rate (PR) of 10.2 per 100000; among them were 186 Arabs, of whom 72 were Palestinians and 51 Kuwaitis. Comparison of these two subgroups, who had a similar age distribution revealed that the disease was 2 1/2 times more frequent among Palestinians (PR 23.8/100000) than among Kuwaitis (PR 9.5/100000). Palestinians also showed significant differences from Kuwaitis in eye color, blood group distribution and HLA-DR and HLA-DQW epitopes frequency. This suggests that genetic rather than environmental factors might be the underlying cause for the high susceptibility to develop MS among Arabs originating from the Eastern Mediterranean basin.

引用

页码：137 / 141

页数：5

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