MIXED ACENANNELLATED METALLOTETRAAZAPORPHINS - A NEW CLASS OF AMPHIPHILIC PHOTOSENSITIZERS FOR THE PHOTODYNAMIC THERAPY OF CANCER

被引：16

作者：

GASPARD, S ^{[1
]}

MARGARON, P ^{[1
]}

TEMPETE, C ^{[1
]}

THU, HTT ^{[1
]}

机构：

[1] CNRS, CEA, DESICP, DLPC, SCM, UA 331, F-91191 GIF SUR YVETTE, FRANCE

来源：

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY | 1990年 / 4卷 / 04期

关键词：

Amphiphilic photosensitizers; photocytotoxicity; photodynamic therapy;

D O I：

10.1016/1011-1344(90)85020-W

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The first synthesis of amphiphilic mixed acenannellated metallotetraazaporphins compounds, designed with the aim of improving cell membrane penetration, is described and the preliminary results on their photocytotoxicity are presented. © 1990.

引用

页码：419 / 423

页数：5

共 23 条

[1] BIOLOGICAL-ACTIVITIES OF PHTHALOCYANINES .10. SYNTHESES AND ANALYSES OF SULFONATED PHTHALOCYANINES [J].

ALI, H ;

LANGLOIS, R ;

WAGNER, JR ;

BRASSEUR, N ;

PAQUETTE, B ;

VANLIER, JE .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1988, 47 (05) :713-717

[2] PHOTOSENSITIZED INACTIVATION OF CHINESE-HAMSTER CELLS BY PHTHALOCYANINES [J].

BENHUR, E ;

ROSENTHAL, I .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1985, 42 (02) :129-133

[3]

Borenfreud E, 1984, METHODS CELL SCI, V9, P7, DOI DOI 10.1007/BF01666038

[4] TOXICITY DETERMINED INVITRO BY MORPHOLOGICAL ALTERATIONS AND NEUTRAL RED ABSORPTION [J].

BORENFREUND, E ;

PUERNER, JA .

TOXICOLOGY LETTERS, 1985, 24 (2-3) :119-124

[5] BIOLOGICAL-ACTIVITIES OF PHTHALOCYANINES .5. PHOTODYNAMIC THERAPY OF EMT-6 MAMMARY-TUMORS IN MICE WITH SULFONATED PHTHALOCYANINES [J].

BRASSEUR, N ;

ALI, H ;

LANGLOIS, R ;

WAGNER, JR ;

ROUSSEAU, J ;

VANLIER, JE .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1987, 45 (05) :581-586

[6] BIOLOGICAL-ACTIVITIES OF PHTHALOCYANINES .3. PHOTOINACTIVATION OF V-79 CHINESE-HAMSTER CELLS BY TETRASULFOPHTHALOCYANINES [J].

BRASSEUR, N ;

ALI, H ;

AUTENRIETH, D ;

LANGLOIS, R ;

VANLIER, JE .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1985, 42 (05) :515-521

[7] BIOLOGICAL-ACTIVITIES OF PHTHALOCYANINES .9. PHOTOSENSITIZATION OF V-79 CHINESE-HAMSTER CELLS AND EMT-6 MOUSE MAMMARY-TUMOR BY SELECTIVELY SULFONATED ZINC PHTHALOCYANINES [J].

BRASSEUR, N ;

ALI, H ;

LANGLOIS, R ;

VANLIER, JE .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1988, 47 (05) :705-711

[8]

BROWN T, 1986, BRIT J CANCER, V53, P435

[9] CELL UPTAKE, DISTRIBUTION AND RESPONSE TO ALUMINUM CHLORO SULFONATED PHTHALOCYANINE, A POTENTIAL ANTITUMOR PHOTOSENSITIZER [J].

CHAN, WS ;

SVENSEN, R ;

PHILLIPS, D ;

HART, IR .

BRITISH JOURNAL OF CANCER, 1986, 53 (02) :255-263

[10] PHOTOSENSITIZERS - THERAPY AND DETECTION OF MALIGNANT-TUMORS [J].

DOUGHERTY, TJ .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1987, 45 (06) :879-889

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