KAINIC ACID AND GLUTAMATE RECEPTOR

被引：98

作者：

HALL, JG ^{[1
]}

HICKS, TP ^{[1
]}

MCLENNAN, H ^{[1
]}

机构：

[1] UNIV BRITISH COLUMBIA,DEPT PHYSIOL,VANCOUVER V6T 1W5,BC,CANADA

来源：

NEUROSCIENCE LETTERS | 1978年 / 8卷 / 02期

关键词：

D O I：

10.1016/0304-3940(78)90192-1

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The excitatory effects of microelectrophoretically administered kainic (KAIN) and glutamic (GLUT) acids have been compared on central neurones of the rat in the presence of antagonists of amino acid-induced excitations. Antagonism by both D-α-amino adipic acid (DAA) and glutamic acid diethyl ester (GDEE) of the effects of glutamic acid but not those of kainic acid suggests that these two excitants elevate neuronal firing rate by interaction with differing receptor populations. © 1978.

引用

页码：171 / 175

页数：5

共 23 条

[1] EFFECTS OF GLUTAMATE, ASPARTATE, AND 2 PRESUMED ANTAGONISTS ON FELINE RUBROSPINAL NEURONS [J].

ALTMANN, H ;

TENBRUGGENCATE, G ;

PICKELMANN, P ;

STEINBERG, R .

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 1976, 364 (03) :249-255

[2] ACUTE EFFECT OF ORAL AND SUBCUTANEOUS ADMINISTRATION OF MONOSODIUM GLUTAMATE ON ARCUATE NUCLEUS OF HYPOTHALAMUS IN MICE AND RATS [J].

BURDE, RM ;

SCHAINKER, B ;

KAYES, J .

NATURE, 1971, 233 (5314) :58-+

[3] GABA RECEPTOR-BINDING IN RAT STRIATUM - LOCALIZATION AND EFFECTS OF DENERVATION [J].

CAMPOCHIARO, P ;

SCHWARCZ, R ;

COYLE, JT .

BRAIN RESEARCH, 1977, 136 (03) :501-511

[4] LESION OF STRIATAL NEURONS WITH KAINIC ACID PROVIDES A MODEL FOR HUNTINGTONS-CHOREA [J].

COYLE, JT ;

SCHWARCZ, R .

NATURE, 1976, 263 (5574) :244-246

[5]

CURTIS DR, 1974, ERG PHYSIOL BIOL CH, V69, P97

[6]

ENGBERG I, 1975, BRIT J PHARMACOL, V55, pP250

[7]

EVANS RH, 1976, J PHYSL LOND, V263, P122

[8] RELEASE OF RADIOLABELED DOPAMINE, SEROTONIN, ACETYLCHOLINE AND GABA FROM SLICES OF RAT STRIATUM AFTER INTRASTRIATAL KAINIC ACID INJECTIONS [J].

FRANKHUYZEN, AL ;

MULDER, AH .

BRAIN RESEARCH, 1977, 135 (02) :368-373

[9]

GUBAREFF TD, 1977, NEUR ABST, V3, P515

[10] FINE-STRUCTURAL CHANGES IN RAT STRIATUM AFTER LOCAL INJECTIONS OF KAINIC ACID [J].

HATTORI, T ;

MCGEER, EG .

BRAIN RESEARCH, 1977, 129 (01) :174-180

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