NITRILES IN HETEROCYCLIC SYNTHESIS - THE REACTION OF POLYHYDRIC NAPHTHALENES, 4-METHYLCOUMARIN-3-CARBONITRILE, AND ALKYLIDENEMALONONITRILE WITH METHYLENEMALONONITRILE

被引：55

作者：

ELAGAMEY, AGA ^{[1
]}

ELTAWEEL, FMA ^{[1
]}

KHODEIR, MNM ^{[1
]}

ELNAGDI, MH ^{[1
]}

机构：

[1] CAIRO UNIV, FAC SCI, DEPT CHEM, GIZA, EGYPT

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN | 1993年 / 66卷 / 02期

关键词：

D O I：

10.1246/bcsj.66.464

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

2-Naphthol and naphthalenediols react with methylenemalononitrile, generated in situ from reaction of formaldehyde and malononitrile, to yield naphthopyrans and naphthodipyrans. 5-Hydroxynaphtho[2,1-b]pyrans reacted further with methylenemalononitrile to yield naphthodipyrans. The reaction of methylenemalononitrile with 4-methylcoumarin-3-carbonitrile afforded benzopyrano[4,3-h]quinoline. 6-Cyanomethyl-3-pyridinecarbonitriles, prepared via reacting 1-arylethylidenemalononitriles with malononitrile, afforded 4H-quinolizines on treatment with methylenemalononitrile.

引用

页码：464 / 468

页数：5

共 14 条

[1]

AWAYA H, 1974, CHEM PHARM BULL, V22, P1424

[2] NITRILES IN HETEROCYCLIC SYNTHESIS - NOVEL SYNTHESES OF BENZO[B]PYRANS, NAPHTHO[1,2-B]PYRANS, NAPHTHO[2,1-B]PYRANS, PYRANO[3,2-H]QUINOLINES AND PYRANO[3,2-C]QUINOLINES [J].