CLEARANCE CONCEPTS IN PHARMACOKINETICS

被引：796

作者：

ROWLAND, M ^{[1
]}

BENET, LZ ^{[1
]}

GRAHAM, GG ^{[1
]}

机构：

[1] UNIV CALIF,SCH PHARM,DEPT PHARM,SAN FRANCISCO,CA 94122

来源：

JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS | 1973年 / 1卷 / 02期

关键词：

D O I：

10.1007/BF01059626

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：123 / 136

页数：14

共 11 条

[1] GENERALIZED SOLUTION TO LINEAR, 2-COMPARTMENT, OPEN MODEL FOR DRUG DISTRIBUTION [J].

BISCHOFF, KB ;

DEDRICK, RL .

JOURNAL OF THEORETICAL BIOLOGY, 1970, 29 (01) :63-&

[2] THIOPENTAL PHARMACOKINETICS [J].

BISCHOFF, KB ;

DEDRICK, RL .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1968, 57 (08) :1346-&

[3] PRELIMINARY MODEL FOR METHOTREXATE PHARMACOKINETICS [J].

BISCHOFF, KB ;

DEDRICK, RL ;

ZAHARKO, DS .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1970, 59 (02) :149-+

[4] APPLICATION OF CLEARANCE AND VOLUME OF DISTRIBUTION TO PLATEAU PRINCIPLE OF DRUGS [J].

CUCINELL, SA ;

PERL, W .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1970, 59 (10) :1423-+

[5] IN-VITRO-IN-VIVO CORRELATION OF DRUG-METABOLISM - DEAMINATION OF 1-BETA-D-ARABINOFURANOSYLCYTOSINE [J].

DEDRICK, RL ;

FORRESTER, DD ;

HO, DHW .

BIOCHEMICAL PHARMACOLOGY, 1972, 21 (01) :1-+

[6] PHARMACOKINETIC BASIS FOR INFLUENCE OF ROUTE OF ADMINISTRATION ON AREA UNDER PLASMA CONCENTRATION-TIME CURVE [J].

GIBALDI, M ;

FELDMAN, S .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1969, 58 (12) :1477-&

[7] EFFECT OF PERFUSION RATE AND DISTRIBUTION FACTORS ON DRUG ELIMINATION KINETICS IN A PERFUSED ORGAN SYSTEM [J].

NAGASHIMA, R ;

LEVY, G .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1968, 57 (11) :1991-+

[8] APPLICATION OF CLEARANCE CONCEPTS TO SOME LITERATURE DATA ON DRUG-METABOLISM IN ISOLATED PERFUSED LIVER PREPARATION AND IN-VIVO [J].

ROWLAND, M .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1972, 17 (03) :352-&

[9] INFLUENCE OF ROUTE OF ADMINISTRATION ON DRUG AVAILABILITY [J].

ROWLAND, M .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1972, 61 (01) :70-&

[10] THE RENAL CLEARANCES OF SUBSTITUTED HIPPURIC ACID DERIVATIVES AND OTHER AROMATIC ACIDS IN DOG AND MAN [J].

SMITH, HW ;

FINKELSTEIN, N ;

ALIMINOSA, L ;

CRAWFORD, B ;

GRABER, M .

JOURNAL OF CLINICAL INVESTIGATION, 1945, 24 (03) :388-404

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