ASYMMETRIC INDUCTION IN RADICAL CYCLIZATION LEADING TO BETA-LACTAMS - FORMAL SYNTHESIS OF (+)-PS-5

被引：0

作者：

ISHIBASHI, H

KAMEOKA, C

SATO, T

IKEDA, M

机构：

来源：

SYNLETT | 1994年 / 06期

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中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Tributyltin hydride-mediated radical cyclization of N-[2,2-bis(phenylthio)ethenyl]-alpha-bromoalkanamides bearing (S)-1-phenylethyl group on the nitrogen atom gave (4S)-4-bis(phenylthio)-methyl-2-azetidinones as major products. The method was applied to the synthesis of a chiral precursor of carbapenem antibiotic (+)-PS-5.

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页码：445 / 446

页数：2

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