N-PROTEIN OF BACTERIOPHAGE-LAMBDA, DEFINED BY ITS DNA-SEQUENCE, IS HIGHLY BASIC

被引：74

作者：

FRANKLIN, NC ^{[1
]}

BENNETT, GN ^{[1
]}

机构：

[1] STANFORD UNIV HOSP,DEPT BIOL SCI,STANFORD,CA 94305

来源：

GENE | 1979年 / 8卷 / 01期

关键词：

E coli phage; Positive regulation by antitermination of transcription; restriction endonucleases;

D O I：

10.1016/0378-1119(79)90011-8

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Nucleotide sequence has been determined for the restriction fragments and cloned DNA from thepL-N-tL1 region of bacteriophage λ. A unique reading frame for the N gene is defined by the absence of natural nonsense codons and by the presence of seven nonsense codons generated by mutations in N. This reading frame is initiated at two alternative ATG codons, the second of which is probably the in vivo translation start. Reading is stopped at a single TAG codon. The protein coded is therefore 133 or, more probably, 107 amino acids long, rich in lysine, arginine and proline. © 1979.

引用

页码：107 / 119

页数：13

共 56 条

[1] RELEASE OF POLARITY IN ESCHERICHIA-COLI BY GENE N OF PHAGE LAMBDA - TERMINATION AND ANTITERMINATION OF TRANSCRIPTION [J].