SPECTROPHOTOMETRIC DETERMINATION OF ACETAMINOPHEN, SALICYLAMIDE AND CODEINE PHOSPHATE IN TABLETS

被引：30

作者：

ELSAYED, MAH ^{[1
]}

BELAL, SF ^{[1
]}

ELWALILY, AFM ^{[1
]}

ABDINE, H ^{[1
]}

机构：

[1] UNIV ALEXANDRIA, FAC PHARM, DEPT PHARMACEUT ANALYT CHEM, ALEXANDRIA, EGYPT

来源：

ANALYST | 1979年 / 104卷 / 1240期

关键词：

Acetaminophen; Codeine phosphate; Salicylamide; Spectrophotometry;

D O I：

10.1039/an9790400620

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

An accurate and simple method is proposed for the analysis of a three-component mixture composed of acetaminophen, salicylamide and codeine phosphate, without the necessity for the previous separation of any component. The first two components are determined directly by independent spectrophotometric measurements, based on the pH-induced spectral changes. Codeine phosphate is assayed by the formation of an ion pair with methyl orange. The procedure has been applied successfully to the analysis of known mixtures and commercial tablets.

引用

页码：620 / 625

页数：6

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