ASYMMETRIC-SYNTHESIS OF SPIROCYCLIC PYRROLIDINES AND TETRAHYDROFURANS BY CHIRAL ALDOL REACTIONS AND PHENYLTHIO MIGRATION

被引：20

作者：

CHIBALE, K ^{[1
]}

WARREN, S ^{[1
]}

机构：

[1] UNIV CAMBRIDGE,CHEM LAB,LENSFIELD RD,CAMBRIDGE CB2 1EW,ENGLAND

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 45期

关键词：

D O I：

10.1016/0040-4039(91)80244-Z

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Highly enantioselective aldol reactions of the boron enolate of (S)-N-propionyl-4-(phenylmethyl)-2-oxazolidinone with alpha-phenylthio cycloalkanecarbaldehydes were achieved. Cyclisation of the chiral phenylthio sulphonamide and diols gave the title compounds in excellent yields and enantiomeric excess.

引用

页码：6645 / 6648

页数：4

共 22 条

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