1ST EVIDENCE OF SPONTANEOUS DEAMIDATION OF GLUTAMINE RESIDUE VIA CYCLIC IMIDE TO ALPHA-GLUTAMIC AND GAMMA-GLUTAMIC RESIDUE UNDER PHYSIOLOGICAL CONDITIONS

被引:31
作者
CAPASSO, S
MAZZARELLA, L
SICA, F
ZAGARI, A
机构
关键词
D O I
10.1039/c39910001667
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
At 37-degrees-C and pH 7.4 the spontaneous deamidation of Gln-peptide proceeds prevalently via a glutarimide intermediate and gives a mixture of alpha-Glu- and gamma-Glu-peptide.
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页码:1667 / 1668
页数:2
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