Making yellow fever American: The early American Republic, the British Empire and the geopolitics of disease in the Atlantic world

Between 1793 and 1822, a series of successive yellow fever outbreaks ravaged the eastern seaboard of the United States. The outbreaks generated not only the biggest public health crisis in that period but also one of the most pressing and contentious disputes in medical theory. Often told as a national story, this article re-examines that controversy by situating it in the context of outbreaks, research, and debates in other parts of the anglophone Atlantic. It argues that American responses to disease were shaped by the young republic's post-imperial relations to both Great Britain and the West Indies. On a broader level, this study challenges current approaches in the formation of American natural knowledge and identity during this period. It looks beyond both national boundaries and relations to former metropolitan centers, locating some of the above developments in a more "multi-centered'' Atlantic world.