BETA-D-GLUCAN CONCENTRATIONS DETECTED BY TOXICOLOR AND ENDOSPECY TESTS IN THE URINE OF PATIENTS WITH URINARY FUNGAL-INFECTIONS

被引:3
|
作者
MATSUMOTO, T
HARAOKA, M
KUBO, S
TAKAHASHI, K
TANAKA, M
OGATA, N
KUMAZAWA, J
机构
[1] Department of Urology, Faculty of Medicine, Kyushu University, Fukuoka, 812, Fukuoka, 3-1-1, Maidashi, Higashi-ku
来源
UROLOGICAL RESEARCH | 1993年 / 21卷 / 02期
关键词
BETA-D-GLUCAN; ENDOSPECY; ENDOTOXIN-G; FUNGURIA; TOXICOLOR;
D O I
10.1007/BF01788829
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Beta-D-glucan is an essential component of the cell wall of fungi. We measured its concentration in the urine of patients with funguria using the chromogenic endotoxin assay kits, Toxicolor and Endospecy. These assay systems use the same Limulus coagulation enzymes. Since the Endospecy test detects endotoxin but not factor G, which is activated by beta-D-glucan, the beta-D-glucan concentration can be calculated by subtracting the Endospecy value from the Toxicolor value. Concentrations of beta-D-glucan were found to be significantly higher in urine samples from patients with funguria (greater-than-or-equal-to 10(3) colony-forming units/ml) than in non-infected samples.
引用
收藏
页码:117 / 120
页数:4
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