N-EPSILON-CARBOXYMETHYLLYSINE FORMATION BY DIRECT ADDITION OF GLYOXAL TO LYSINE DURING THE MAILLARD REACTION

被引：23

作者：

ALABED, Y

BUCALA, R

机构：

[1] The Picower Institute For Medical Research, Manhasset, NY 11030

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1995年 / 5卷 / 18期

关键词：

D O I：

10.1016/0960-894X(95)00375-4

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Glyoxal, a retro-aldol cleavage product of the Maillard reaction, is a likely intermediate for the formation of N-epsilon-carboxymethyllysine upon incubation with lysine under physiological conditions.

引用

页码：2161 / 2162

页数：2

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BUCALA, R .

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