LIPID-INDEPENDENT THERAPEUTIC PROPERTIES OF TRANSDERMAL-17 B-ESTRADIOL ON CARDIOVASCULAR-DISEASES

被引：9
作者：
CAGNACCI, A
SOLDANI, R
PUCCINI, E
FIORETTI, P
MELIS, GB
机构：
[1] DEPT OBSTET & GYNECOL,CAGLIARI,ITALY
[2] DEPT OBSTET & GYNECOL,PISA,ITALY
[3] DEPT CARDIOVASC DIS,PISA,ITALY
来源：
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA | 1992年 / 71卷 / 08期
关键词：
ESTRADIOL; CARDIOVASCULAR DISEASE; HEART; LIPID; BLOOD PRESSURE; MENOPAUSE;
D O I：
10.3109/00016349209006235
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
A low dose of transdermally administered 17 B-estradiol promptly improved a severe, treatment-unresponsive, cardiac arrhythmia initiated after the menopause in a woman with type-II familial hyperlipoproteinemia. The same treatment normalized the hypertension initiated after ovariectomy, in a woman who was only poorly controlled by anti-hypertensive drugs. These two cases are the first clear report of cardiovascular therapeutic properties of transdermal estradiol via mechanisms independent of lipoprotein modifications.
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收藏
页码：639 / 641
页数：3
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