CARDIORESPIRATORY CONTROL IN AN INFANT WITH ONDINES CURSE - A MULTIVARIATE AUTOREGRESSIVE MODELING APPROACH

被引：22

作者：

OGAWA, T ^{[1
]}

KOJO, M ^{[1
]}

FUKUSHIMA, N ^{[1
]}

SONODA, H ^{[1
]}

GOTO, K ^{[1
]}

ISHIWA, S ^{[1
]}

ISHIGURO, M ^{[1
]}

机构：

[1] INST STAT MATH,MINATO KU,TOKYO,JAPAN

来源：

JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM | 1993年 / 42卷 / 01期

关键词：

MULTIVARIATE AUTOREGRESSIVE MODE; ONDINES CURSE; CARDIORESPIRATORY CONTROL; NOISE CONTRIBUTION RATIO; IMPULSE AND FREQUENCY RESPONSE;

D O I：

10.1016/0165-1838(93)90340-Z

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We applied spectral analysis through multivariant autoregressive model fitting [1] to RR interval (RRI) and respiratory (RES) oscillation obtained during quiet sleep in an infant with congenital central hypoventilation syndrome (Ondine's curse), a child with obstructive sleep apnea, and two healthy children. Power spectra, impulse response and noise contribution ratio between RRI and RES oscillation were calculated by using a minicomputer PFU-1200 (FACOM) to determine the structure of the feedback system between RRI and RES within the central nervous system. We found that the respiratory noise contribution ratio to RRI was significantly smaller in Ondine's curse (37 +/- 7.7%, at 0.23 Hz) than in obstructive sleep apnea (90 +/- 6.7%, at 0.39 Hz) and healthy subjects. We postulate that the result shows disturbance of the central autonomic control of breathing and heart rate in Ondine's curse.

引用

页码：41 / 51

页数：11

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