EFFECTS OF ZN2+ ON UPTAKE OF CA2+, SR2+ AND BA2+ BY BONE POWDER AND ANORGANIC BONE

被引：1
作者：
SAMACHSON, J
SCHMITZ, A
机构：
[1] Metabolic Section, Veterans Administration Hospital, Hines, IL
[2] University of Illinois, College of Medicine, Chicago, IL
来源：
BIOCHIMICA ET BIOPHYSICA ACTA | 1969年 / 192卷 / 02期
关键词：
D O I：
10.1016/0304-4165(69)90360-2
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
1. 1. The presence of 2.5 mmoles/1 of stable Zn2+ increases the uptake of 85Sr2+ and 133Ba2+ by bone powder and by anorganic bone from solutions that contain these radioisotopes in tracer quantities, whereas the presence of stable Ca2+ or Ba2+ decreases uptake. The presence of stable Ca2+ or Ba2+ does not appreciably affect the uptake of tracer quantities of 65Zn2+. 2. 2. The results support the hypothesis that Zn2+ distorts the surface of the crystals of bone mineral and thus facilities the replacement of Ca2+ by larger alkaline earth ions. The effect is found when tracer amounts of the alkaline earth ions are used but not when the concentrations of these ions are of the order of 2.5 mmoles/l. © 1969.
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页码：238 / +
页数：1
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