IN-VITRO EVALUATION OF THE ACTIVITIES OF AZITHROMYCIN ALONE AND COMBINED WITH PYRIMETHAMINE AGAINST TOXOPLASMA-GONDII

被引：28
作者：
CANTIN, L
CHAMBERLAND, S
机构：
[1] CHU LAVAL,CTR RECH,LAB SERV INFECTIOL,QUEBEC CITY G1V 4G2,QUEBEC,CANADA
[2] UNIV LAVAL,FAC MED,DEPT MICROBIOL,QUEBEC CITY G1V 4G2,QUEBEC,CANADA
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1993年 / 37卷 / 09期
关键词：
D O I：
10.1128/AAC.37.9.1993
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
By using an in vitro microassay to assess drug interaction, azithromycin combined to pyrimethamine was found more active than pyrimethamine alone against Toxoplasma gondii, and additivity between those drugs was demonstrated. Our results show that the combination of azithromycin and pyrimethamine may lead to a more rapid control of T. gondii.
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页码：1993 / 1996
页数：4
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