A STUDY OF THE USE OF MICRODIALYSIS PROBES AS A SAMPLING UNIT IN ONLINE BIOPROCESS MONITORING IN CONJUNCTION WITH COLUMN LIQUID-CHROMATOGRAPHY

被引：31

作者：

MARKOVARGA, G ^{[1
]}

BUTTLER, T ^{[1
]}

GORTON, L ^{[1
]}

GRONSTERWALL, C ^{[1
]}

机构：

[1] CMA MICRODIALYSIS AB,S-22370 LUND,SWEDEN

来源：

CHROMATOGRAPHIA | 1993年 / 35卷 / 5-6期

关键词：

COLUMN LIQUID CHROMATOGRAPHY; MICRODIALYSIS; FERMENTATION MONITORING;

D O I：

10.1007/BF02277511

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

An automated on-line sampling and analytical set-up for the control of fermentations was studied incorporating a microdialysis probe as the sampling device. Applications to a penicillin broth and an ethanol fermentation were studied. Typical recovery values of carbohydrates were found to be close to 100% even after exposure of the microdialysis probe in the process for about 30 h.

引用

页码：285 / 289

页数：5

共 18 条

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