A STUDY OF THE USE OF MICRODIALYSIS PROBES AS A SAMPLING UNIT IN ONLINE BIOPROCESS MONITORING IN CONJUNCTION WITH COLUMN LIQUID-CHROMATOGRAPHY

被引：31
作者：
MARKOVARGA, G [1 ]
BUTTLER, T [1 ]
GORTON, L [1 ]
GRONSTERWALL, C [1 ]
机构：
[1] CMA MICRODIALYSIS AB,S-22370 LUND,SWEDEN
来源：
CHROMATOGRAPHIA | 1993年 / 35卷 / 5-6期
关键词：
COLUMN LIQUID CHROMATOGRAPHY; MICRODIALYSIS; FERMENTATION MONITORING;
D O I：
10.1007/BF02277511
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
An automated on-line sampling and analytical set-up for the control of fermentations was studied incorporating a microdialysis probe as the sampling device. Applications to a penicillin broth and an ethanol fermentation were studied. Typical recovery values of carbohydrates were found to be close to 100% even after exposure of the microdialysis probe in the process for about 30 h.
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页码：285 / 289
页数：5
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