The Role of Non-Steroidal Anti-Inflammatory Drugs in Renal Colic

被引：27
|
作者：
Davenport, Kim [1 ]
Waine, Elizabeth [1 ]
机构：
[1] Southmead Hosp, Bristol Urol Inst, Bristol BS10 5NB, Avon, England
来源：
PHARMACEUTICALS | 2010年 / 3卷 / 05期
关键词：
renal colic; ureteric stone; Non-steroidal anti-inflammatory drugs;
D O I：
10.3390/ph3051304
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
NSAIDs provide optimal analgesia in renal colic due to the reduction in glomerular filtration and renal pelvic pressure, ureteric peristalsis and ureteric oedema. Prevention of glomerular afferent arteriolar vasodilatation renders these patients at risk of renal impairment. NSAIDs have the additional benefit of reducing the number of new colic episodes and preventing subsequent readmission to hospital. Despite recent work promoting the use of pharmacological agents to improve stone passage rates, NSAIDs do not appear to reduce the time to stone passage or increase the likelihood of stone passage in renal colic.
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页码：1304 / 1310
页数：7
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