PARALLEL INVESTIGATIONS OF THE EFFECTS OF ADENOSINE ON EVOKED-POTENTIALS AND CYCLIC-AMP ACCUMULATION IN HIPPOCAMPUS SLICES OF THE RAT

被引：38

作者：

REDDINGTON, M

SCHUBERT, P

机构：

[1] Max-Planck-Institute for Psychiatry, 8000 Munich 40

来源：

NEUROSCIENCE LETTERS | 1979年 / 14卷 / 01期

关键词：

D O I：

10.1016/0304-3940(79)95340-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In slices of rat hippocampus, adenosine and its receptor agonist, 2-chloro-adenosine, were both found to (a) enhance the intracellular accumulation of cyclic adenosine monophosphate (cAMP) and (b) depress neuronal evoked responses to electrical stimulation. The differences in the dose/effect curves for the biochemical and electrophysiological changes cast doubt on a causal relationship between the two effects. © 1979.

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页码：37 / 42

页数：6

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