ADJUNCTIVE CHEMOTHERAPY OF INFECTION-INDUCED STAGHORN CALCULI

被引：54

作者：

GRIFFITH, DP

MOSKOWITZ, PA

CARLTON, CE

机构：

[1] BAYLOR UNIV,COLL MED,DIV UROL,HOUSTON,TX 77025

[2] BAYLOR UNIV,COLL MED,ROY & LILLIE CULLEN DEPT UROL RES,J SAYLES LEACH LAB,HOUSTON,TX 77025

[3] VET ADM HOSP,UROL SERV,HOUSTON,TX 77211

来源：

JOURNAL OF UROLOGY | 1979年 / 121卷 / 06期

关键词：

D O I：

10.1016/S0022-5347(17)56964-5

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Bacteria induce urinary crystallization of struvite and carbonate-apatite as a by-product of ureolysis by urease. Eradication of infection and/or inhibition of urease with acetohydroxamic acid for 5 to 30 months retarded stone growth and brought about partial or complete dissolution of stones in 9 patients. Long-term chemotherapy with antimicrobial agents that achieve sterile urine or acetohydroxamic acid in those patients with recalcitrant infection lessens the risk of recurrent calculogenesis.

引用

页码：711 / 715

页数：5

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