A DIRECT METHOD FOR THE SYNTHESIS OF POLYFUNCTIONALIZED UNSATURATED CARBONYL DERIVATIVES BY MICHAEL ADDITION OF NITROALKANES TO ENEDIONES WITH THE HELP OF DBU

被引：62

作者：

BALLINI, R

BOSICA, G

机构：

[1] Dipartimento di Scienze Chimiche dell'Università, I-62032 Camerino

来源：

TETRAHEDRON | 1995年 / 51卷 / 14期

关键词：

D O I：

10.1016/0040-4020(95)00136-V

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Michael addition of several nitroalkanes to dimethyl maleate, (Z)-3-hexene-2,5-dione, N-ethyl maleimide, and N-phenyl maleimide, in MeCN or THF, proceeds very efficiently on DBU as base, and furnishes good to high yields of polyfunctionalized or saturated carbonyl derivatives.

引用

页码：4213 / 4222

页数：10

共 18 条

[1]

APSIMON J, 1988, TOTAL SYNTHESIS NATU

[2] MICHAEL ADDITION OF NITROALKANES TO DIMETHYL MALEATE WITH DBU - A NEW DIRECT METHOD FOR THE SYNTHESIS OF POLYFUNCTIONALIZED ALPHA,BETA-UNSATURATED ESTERS [J].

BALLINI, R ;

RINALDI, A .

TETRAHEDRON LETTERS, 1994, 35 (49) :9247-9250

[3]

BALLINI R, 1987, SYNTHESIS-STUTTGART, P71

[4]

BERGMAN ED, 1959, ORG REACTIONS, V10, P779

[5]

CLOUGH JM, 1991, COMPREHENSIVE ORGANI, V3, P861

[6]

Corey E J, 1989, LOGIC CHEM SYNTHESIS

[7]

Demuth M., 1991, COMPREHENSIVE ORGANI, V5, P215, DOI DOI 10.1016/B978-0-08-052349-1.00125-6

[8] STEREOSELECTIVE SYNTHESIS OF SUBSTITUTED OXETANES [J].

GALATSIS, P ;

PARKS, DJ .

TETRAHEDRON LETTERS, 1994, 35 (36) :6611-6614

[9]

HWU JR, 1992, TETRAHEDRON LETT, V33, P6469

[10]

Lee V. J., 1991, COMPREHENSIVE ORGANI, V4, P69

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