CUCURBITACINS WITH UNUSUAL SIDE-CHAINS FROM PICRORHIZA-KURROA

被引：25

作者：

STUPPNER, H ^{[1
]}

MULLER, EP ^{[1
]}

机构：

[1] UNIV INNSBRUCK, INST ORGAN & PHARMAZEUT CHEM, A-6020 INNSBRUCK, AUSTRIA

来源：

PHYTOCHEMISTRY | 1993年 / 33卷 / 05期

关键词：

PICRORHIZA-KURROA; SCROPHULARIACEAE; ROOTS; CUCURBITACIN GLYCOSIDES;

D O I：

10.1016/0031-9422(93)85038-S

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

From the roots of Picrorhiza kurroa six new cucurbitacin glycosides, (2beta,9beta,10alpha,16alpha,20xi,24xi)-20,24-epoxy-2-(beta-D-glucopyranosyloxy)-16,25-dihydroxy-9-methyl-19-norlanost-5-ene-3,11-dione, (2beta,3beta,9beta,10alpha,16alpha,20xi,24xi)-20,24-epoxy-24beta-D-glucopyranosyloxy)-3,16,25-trihydroxy-9-methyl-19-norlanost-5-en-11-one, (2beta,9beta,10alpha,16alpha,20xi,24xi)-20,24-epoxy-24beta-D-glucopyranosyloxy)-16,25,26-trihydroxy-9-methyl-19-norlanost-5-ene-3,11-dione, (2beta,3beta,9beta,10alpha, 16alpha,20xi,24xi)-20,24-epoxy-2-(beta-D-glucopyranosyloxy)-3,16,25,26-tetrahydroxy-9-methyl-19-norlanost-5-en-11-one, (2beta,9beta,10alpha,16alpha,20beta,24Z)-24beta-D-glucopyranosyloxy)-16,20,26-trihydroxy-9-methyl-19-norlanost-5,24-diene-3,11-dione and (2beta,9beta,10alpha,16alpha,20beta,24Z)-2-(beta-D-glucopyranosyloxy)-3,16,20,26-tetrahydroxy-9-methyl-19-norlanost-5,24-diene-11-one have been isolated. Their structures were established by usual spectroscopic and two-dimensional (2D) NMR techniques (COSY, HMQC and HMBC).

引用

页码：1139 / 1145

页数：7

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