CUCURBITACINS WITH UNUSUAL SIDE-CHAINS FROM PICRORHIZA-KURROA

被引：25
|
作者：
STUPPNER, H [1 ]
MULLER, EP [1 ]
机构：
[1] UNIV INNSBRUCK, INST ORGAN & PHARMAZEUT CHEM, A-6020 INNSBRUCK, AUSTRIA
来源：
PHYTOCHEMISTRY | 1993年 / 33卷 / 05期
关键词：
PICRORHIZA-KURROA; SCROPHULARIACEAE; ROOTS; CUCURBITACIN GLYCOSIDES;
D O I：
10.1016/0031-9422(93)85038-S
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
From the roots of Picrorhiza kurroa six new cucurbitacin glycosides, (2beta,9beta,10alpha,16alpha,20xi,24xi)-20,24-epoxy-2-(beta-D-glucopyranosyloxy)-16,25-dihydroxy-9-methyl-19-norlanost-5-ene-3,11-dione, (2beta,3beta,9beta,10alpha,16alpha,20xi,24xi)-20,24-epoxy-24beta-D-glucopyranosyloxy)-3,16,25-trihydroxy-9-methyl-19-norlanost-5-en-11-one, (2beta,9beta,10alpha,16alpha,20xi,24xi)-20,24-epoxy-24beta-D-glucopyranosyloxy)-16,25,26-trihydroxy-9-methyl-19-norlanost-5-ene-3,11-dione, (2beta,3beta,9beta,10alpha, 16alpha,20xi,24xi)-20,24-epoxy-2-(beta-D-glucopyranosyloxy)-3,16,25,26-tetrahydroxy-9-methyl-19-norlanost-5-en-11-one, (2beta,9beta,10alpha,16alpha,20beta,24Z)-24beta-D-glucopyranosyloxy)-16,20,26-trihydroxy-9-methyl-19-norlanost-5,24-diene-3,11-dione and (2beta,9beta,10alpha,16alpha,20beta,24Z)-2-(beta-D-glucopyranosyloxy)-3,16,20,26-tetrahydroxy-9-methyl-19-norlanost-5,24-diene-11-one have been isolated. Their structures were established by usual spectroscopic and two-dimensional (2D) NMR techniques (COSY, HMQC and HMBC).
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页码：1139 / 1145
页数：7
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