UPDATE OF THE TOPICAL TREATMENT OF PSORIASIS

被引：24

作者：

Carrascosa, J. M. ^{[1
]}

Vanaclocha, F. ^{[2
]}

Borrego, L. ^{[3
]}

Fernandez-Lopez, E. ^{[4
]}

Fuertes, A. ^{[5
]}

Rodriguez-Fernandez-Freire, L. ^{[6
]}

Zulaica, A. ^{[7
]}

Tuneu, A. ^{[8
]}

Caballe, G. ^{[9
]}

Colome, E. ^{[9
]}

Bordas, X. ^{[10
]}

Hernanz, J. M. ^{[11
]}

Brufau, C. ^{[12
]}

Herrera, E. ^{[13
]}

机构：

[1] Hosp Badalona Germans Trias & Pujol, Serv Dermatol, Barcelona 08916, Spain

[2] Hosp 12 Octubre, Serv Dermatol, Madrid, Spain

[3] Hosp Univ Insular Gran Canaria, Las Palmas Gran Canaria, Spain

[4] Hosp Univ Salamanca, Serv Dermatol, Salamanca, Spain

[5] Hosp Univ Dr Peset, Serv Dermatol, Valencia, Spain

[6] Hosp Univ Sevilla, Serv Dermatol, Seville, Spain

[7] Complejo Hosp Univ Vigo, Serv Dermatol, Vigo, Spain

[8] Hosp Donostia San Sebastian, San Sebastian, Spain

[9] LEO Pharma, Barcelona, Spain

[10] Ciutat Univ Bellvitge, Barcelona, Spain

[11] Hosp Infanta Leonor, Secc Dermatol, Madrid, Spain

[12] Hosp Gen Univ Reina Sofia, Secc Dermatol, Murcia, Spain

[13] Hosp Clin, Secc Dermatol, Malaga, Spain

来源：

ACTAS DERMO-SIFILIOGRAFICAS | 2009年 / 100卷 / 03期

关键词：

psoriasis; topical treatment; therapy;

D O I：

10.1016/S0001-7310(09)70534-4

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Topical therapy continues to be one of the pillars of psoriasis management. Topical corticosteroids and vitamin D analogs are the drugs of choice during the induction phase, and vitamin D analogs continue to be drugs of choice for maintenance therapy. Tazarotene and dithranol are suitable options in patients with certain, specific characteristics. The calcineurin inhibitors can be considered to be second-line treatment for psoriasis of the face and flexures. The efficacy and safety of the fixed-dose combination of betamethasone and calcipotriol in the induction phase is greater than that of either drug alone. The combination of corticosteroids with salicylic acid achieves better results than corticosteroids in monotherapy. None of the drugs evaluated stands out over the others in all clinical situations, and their use must therefore be individualized in each patient and adjusted according to the course of the disease.

引用

页码：190 / 200

页数：11

共 61 条

[1] Retrospective assessment of PASI 50 and PASI 75 attainment with a calcipotriol/betamethasone dipropionate ointment [J].

Anstey, Alex V. ;

Kragballe, Knud .

INTERNATIONAL JOURNAL OF DERMATOLOGY, 2006, 45 (08) :970-975

[2] Systematic review of comparative efficacy and tolerability of calcipotriol in treating chronic plaque psoriasis [J].

Ashcroft, DM ;

Po, ALW ;

Williams, HC ;

Griffiths, CEM .

BMJ-BRITISH MEDICAL JOURNAL, 2000, 320 (7240) :963-967

[3] URINE CALCIUM EXCRETION DURING TREATMENT OF PSORIASIS WITH TOPICAL CALCIPOTRIOL [J].

BERTHJONES, J ;

BOURKE, JF ;

IQBAL, SJ ;

HUTCHINSON, PE .

BRITISH JOURNAL OF DERMATOLOGY, 1993, 129 (04) :411-414

[4] A MULTICENTER, PARALLEL-GROUP COMPARISON OF CALCIPOTRIOL OINTMENT AND SHORT-CONTACT DITHRANOL THERAPY IN CHRONIC PLAQUE PSORIASIS [J].

BERTHJONES, J ;

CHU, AC ;

DODD, WAH ;

GANPULE, M ;

GRIFFITHS, WAD ;

HAYDEY, RP ;

KLABER, MR ;

MURRAY, SJ ;

ROGERS, S ;

JURGENSEN, HJ .

BRITISH JOURNAL OF DERMATOLOGY, 1992, 127 (03) :266-271

[5]

Bourke JF, 1997, ACTA DERM-VENEREOL, V77, P228

[6] Combination of calcipotriene (Dovonex) ointment and tazarotene (Tazorac) gel versus clobetasol ointment in the treatment of plaque psoriasis: A pilot study [J].

Bowman, PH ;

Maloney, JE ;

Koo, JYM .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2002, 46 (06) :907-913

[7]

Brualla DA, 2003, ACTAS DERMOSIFILI S1, V94, P66

[8]

Camarasa JM, 2003, DERMATOLOG TREAT, V14, P8

[9] A prospective evaluation of the cost of psoriasis in Spain (EPIDERMA project:: Phase II) [J].

Carrascosa, J. M. ;

Pujol, R. ;

Dauden, E. ;

Hernanz-Hermosa, J. M. ;

Bordas, X. ;

Smandia, J. A. ;

Ferrandiz, C. .

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2006, 20 (07) :840-845

[10] CONSENSUS DOCUMENT ON PHOTOTHERAPY: PUVA THERAPY AND NARROW-BAND UVB THERAPY [J].

Carrascosa, Jose M. ;

Gardeazbal, Jesus ;

Perez-Ferriols, Amparo ;

Alomard, Agustin ;

Manrique, Pilar ;

Jones-Caballero, Maria ;

Lecha, Mario ;

Aguilera, Jose ;

de la Cuadra, Jesus .

ACTAS DERMO-SIFILIOGRAFICAS, 2005, 96 (10) :635-658

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