DISTRIBUTION OF DOPAMINE-D2 RECEPTOR MESSENGER-RNA SPLICE VARIANTS IN THE RAT BY SOLUTION HYBRIDIZATION/PROTECTION ASSAY

被引：37
作者：
SNYDER, LA
ROBERTS, JL
SEALFON, SC
机构：
[1] CUNY MT SINAI SCH MED, DR ARTHUR M FISHBERG CTR NEUROBIOL, BOX 1065, 1 GUSTAVE L LEVY PL, NEW YORK, NY 10029 USA
[2] CUNY MT SINAI SCH MED, DEPT NEUROL, NEW YORK, NY 10029 USA
来源：
NEUROSCIENCE LETTERS | 1991年 / 122卷 / 01期
关键词：
SUBTYPE; BRAIN; PITUITARY; SOLUTION-HYBRIDIZATION; POLYMERASE CHAIN REACTION;
D O I：
10.1016/0304-3940(91)90187-X
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
We investigated the distribution of the two dopamine D2 receptor mRNA splice variants in the rat using a sensitive and quantitative solution hybridization/nuclease protection assay. In all brain and endocrine regions studied, both splice variants were detected and the mRNA of the longer form (D2L) was more abundant than that of the shorter form (D2S). The lowest percentages of D2S were found in the pituitary and adrenal glands.
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页码：37 / 40
页数：4
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