INVITRO TESTING OF AN INDIRECT MUTAGEN (CYCLOPHOSPHAMIDE) WITH HUMAN LEUKOCYTE-CULTURES - ACTIVATION WITH LIVER-MICROSOMES AND USE OF A DIALYSIS BAG

被引：34

作者：

MADLE, S ^{[1
]}

OBE, G ^{[1
]}

机构：

[1] FREE UNIV BERLIN,INST GENET,D-1000 BERLIN 33,FED REP GER

来源：

MUTATION RESEARCH | 1977年 / 56卷 / 01期

关键词：

D O I：

10.1016/0027-5107(77)90250-0

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

引用

页码：101 / 103

页数：3

共 18 条

[1] CARCINOGENS ARE MUTAGENS - SIMPLE TEST SYSTEM COMBINING LIVER HOMOGENATES FOR ACTIVATION AND BACTERIA FOR DETECTION [J].

AMES, BN ;

DURSTON, WE ;

YAMASAKI, E ;

LEE, FD .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1973, 70 (08) :2281-2285

[2]

BIMBOES D, 1976, MUTAT RES, V35, P155

[3]

BROCK N, 1963, ARZNEIMITTEL-FORSCH, V13, P1021

[4] MUTAGENIC ACTIVITY OF CYCLOPHOSPHAMIDE, IFOSFAMIDE, AND TROFOSFAMIDE IN DIFFERENT GENES OF ESCHERICHIA-COLI AND SALMONELLA-TYPHIMURIUM AFTER BIOTRANSFORMATION THROUGH EXTRACTS OF RODENT LIVER [J].

ELLENBERGER, J ;

MOHN, G .

ARCHIVES OF TOXICOLOGY, 1975, 33 (03) :225-240

[5]

Hampel K E, 1968, Int Z Klin Pharmakol Ther Toxikol, V1, P322

[6] QUANTITATIVE ANALYSIS OF CHROMOSOME MUTATIONS IN HUMAN LEUKOCYTES INDUCED BY CYCLOPHOSPHAMIDE AFTER ACTIVATION BY LIVER SLICES [J].

HAMPEL, KE ;

FRITZSCH.M ;

STOPIK, D .

HUMANGENETIK, 1969, 7 (01) :28-&

[7] INDUCTION OF POINT MUTATIONS BY DIFFERENT CHEMICAL MECHANISMS IN LIVER MICROSOMAL ASSAY [J].

HERBOLD, B ;

BUSELMAIER, W .

MUTATION RESEARCH, 1976, 40 (02) :73-83

[8] MUTAGENICITY OF CHLORACETALDEHYDE, A POSSIBLE METABOLIC PRODUCT OF 1,2-DICHLOROETHANE (ETHYLENE DICHLORIDE), CHLOROETHANOL (ETHYLENE CHLOROHYDRIN), VINYL-CHLORIDE, AND CYCLOPHOSPHAMIDE [J].

MCCANN, J ;

SIMMON, V ;

STREITWIESER, D ;

AMES, BN .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1975, 72 (08) :3190-3193

[9] NONRANDOM DISTRIBUTION OF CYCLOPHOSPHAMIDE-INDUCED CHROMOSOME BREAKS [J].

MORAD, M ;

ELZAWAHRI, M .

MUTATION RESEARCH, 1977, 42 (01) :125-130

[10] CYTOGENETIC EFFECTS OF MUTAGENS-CARCINOGENS AFTER ACTIVATION IN A MICROSOMAL SYSTEM INVITRO .1. INDUCTION OF CHROMOSOME-ABERRATIONS AND SISTER CHROMATID EXCHANGES BY DIETHYLNITROSAMINE (DEN) AND DIMETHYLNITROSAMINE (DMN) IN CHO CELLS IN PRESENCE OF RAT-LIVER MICROSOMES [J].

NATARAJAN, AT ;

TATES, AD ;

VANBUUL, PPW ;

MEIJERS, M ;

DEVOGEL, N .

MUTATION RESEARCH, 1976, 37 (01) :83-90

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