Inflammatory Myofibroblastic Tumor of Thigh: A Case Report and Review of Literature

Inflammatory myofibroblastic tumor (IMT) is a rarely reported tumor of unknown etiology and pathogenesis. Neoplastic growths of myofibroblast, on a background of plasma cell and lymphocytic proliferation, have been designated as IMT. It occurs primarily in the lungs but has occurred in other extra-pulmonary sites, also. Abdomen is the most common extra-pulmonary site. The biological behavior is still uncertain. We report a case of 56-year-old man presenting with a lump over left thigh for 6 months. Post-excision histopathological examination showed possibility of IMT or spindle cell sarcoma. Immunohistochemical examination showed CD34, S-100, bcl2, and ALK1 negative, also smooth muscle actin positive focally and KI67 positive focally 30% favoring IMT.