XEROSIS: A DYSFUNCTION OF THE EPIDERMAL BARRIER

被引：1

作者：

Barco, D. ^{[1
]}

Gimenez-Arnau, A. ^{[2
]}

机构：

[1] Hosp Santa Creu & Sant Pau, Serv Dermatol, Barcelona, Spain

[2] Hosp Mar, IMIM, Dept Dermatol, Barcelona, Spain

来源：

ACTAS DERMO-SIFILIOGRAFICAS | 2008年 / 99卷 / 09期

关键词：

xerosis; dry skin; stratum corneum; ceramides; lipids;

D O I：

暂无

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Xerosis or dry skin is a common skin disorder among the general population. It is characterized clinically by rough, scaly, and often itchy skin. This disorder is present in the course of some dermatoses such as atopic dermatitis, although it can also occur in healthy individuals if a combination of certain etiologic factors is present. It is characterized pathophysiologically by a disrupted stratum corneum, dehydration, and impaired keratinocyte differentiation. Treatment of xerosis should seek to restore physiologic lipids in the epidermis and provide substances that facilitate epidermal differentiation.

引用

页码：671 / 682

页数：12

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