SYNTHESIS AND SOME REACTIONS OF 8-TERT-BUTYL-6-HYDROXY-4-METHYL COUMARIN

被引：0
|
作者：
ELFARARGY, AF
机构：
来源：
JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN | 1991年 / 13卷 / 01期
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The synthesis of 8-tert-butyl-6-hydroxy-4-methyl coumarin (2) was described. The nitration of compound (2) followed by reduction gave the amino coumarin derivative (5). The latter compound condensed with acetic acid in presence of P2O5 to give the benzoxazole derivative (6). Also the compound (5) reacted with CS2 in presence of KOH/CH3OH to afford the benzoxazol-2-thione derivative (7). It has been found that the coumarin derivative (2) reacted with Grignard reagent by 1,4 addition to give the products (8a,b).
引用
收藏
页码：59 / 62
页数：4
相关论文
共 50 条
  • [41] Synthesis of 7-hydroxy-4-methyl coumarin catalyzed by 12-tungstophosphoric acid
    Zhang, Weihong
    Wu, Shanshan
    Wang, Jun
    Ren, Xiaoqian
    Shiyou Huagong/Petrochemical Technology, 2008, 37 (06): : 597 - 601
  • [42] Synthesis of 7-hydroxy-4-methyl coumarin using polyaniline supported acid catalyst
    Palaniappan, S
    Shekhar, RC
    JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, 2004, 209 (1-2) : 117 - 124
  • [43] SYNTHESIS AND STERIC STRUCTURE OF CIS-ISOMERS AND TRANS-ISOMERS OF 3-METHYL-1-TERT-BUTYL-4-ACETYLPIPERIDOLES-4 AND 3-METHYL-1-TERT-BUTYL-4-CARBOMETHOXYPIPERIDOLES-4
    UNKOVSKII, BV
    SOKOLOVA, TD
    MALINA, YF
    ROMANOVA, KI
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1973, (12): : 1659 - 1665
  • [44] 2,4-Di-tert-butyl-6-(4-nitrophenylimino-methyl) phenol
    Sun, Yi-Feng
    Wang, Xin-Li
    Ma, Shi-Ying
    Chen, Hong-Ji
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2007, 63 : O3746 - U2457
  • [45] 2-tert-butyl-4-methyl-6-(1-piperidiniomethyl)phenol perchlorate
    Zhao, XJ
    Du, M
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2003, 59 : O1161 - O1162
  • [46] STRUCTURAL DIAGRAMS OF 4-METHYLPHENOL-6-TERT-BUTYL-4-METHYLPHENOL, 4-METHYLPHENOL-2,6-DI-TERT-BUTYL-4-METHYLPHENOL AND 6-TERT-BUTYL-4-METHYLPHENOL-2,6-DI-TERT-BUTYL-4-METHYLPHENOL SYSTEMS
    GORODETSKII, ET
    IZVESTIYA VYSSHIKH UCHEBNYKH ZAVEDENII KHIMIYA I KHIMICHESKAYA TEKHNOLOGIYA, 1981, 24 (03): : 383 - 384
  • [47] HETEROPOLYACIDS AS CATALYSTS FOR SYNTHESIS OF METHYL TERT-BUTYL ETHER
    MAKSIMOV, GM
    KOZHEVNIKOV, IV
    REACTION KINETICS AND CATALYSIS LETTERS, 1989, 39 (02): : 317 - 322
  • [48] Synthesis and Antifungal Activity of Some 6-tert-butyl-8-chloro-2, 3-dimethylquinolin-4-ol Derivatives against Pyricularia oryae
    Fang, Yue-Ming
    Zhang, Rui-Rui
    Shen, Zhong-Hua
    Tan, Cheng-Xia
    Weng, Jian-Quan
    Xu, Tian-Ming
    Liu, Xing-Hai
    Huang, Hong-Ying
    Wu, Hong-Ke
    LETTERS IN DRUG DESIGN & DISCOVERY, 2018, 15 (12) : 1314 - 1318
  • [49] THE CHLORINATION OF 2-TERT-BUTYL-4-CHLORO-6-METHYLPHENOL - SOME REACTIONS OF CHLORINE AND NITROGEN-DIOXIDE WITH 6-CHLOROCYCLOHEXA-2,4-DIENONES DERIVED FROM 2-TERT-BUTYL-4-CHLORO-6-METHYLPHENOL
    HARTSHORN, MP
    RODDICK, AD
    STEEL, PJ
    WRIGHT, GJ
    AUSTRALIAN JOURNAL OF CHEMISTRY, 1992, 45 (04) : 721 - 730
  • [50] STRUCTURE OF 2-TERT-BUTYL-6-METHYL-1,6A-LAMBDA-4-DITHIA-6-AZAPENTALENE
    BOEYENS, JCA
    DENNER, L
    MARKWELL, AJ
    REID, DH
    ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 1987, 43 : 1384 - 1386
12345