MENOPAUSAL FLUSHES - NEURO-ENDOCRINE LINK WITH PULSATILE LUTEINIZING-HORMONE SECRETION

被引:231
作者
CASPER, RF [1 ]
YEN, SSC [1 ]
WILKES, MM [1 ]
机构
[1] UNIV CALIF SAN DIEGO,SCH MED,DEPT REPROD MED,LA JOLLA,CA 92093
关键词
D O I
10.1126/science.462193
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Menopausal flush episodes were found to be invariably associated with the initiation of pulsatile pituitary release of luteinizing hormone. This was not accompanied by a significant change in circulating catecholamine or prolactin concentrations. Since pulsatile luteinizing hormone release results from episodic secretion of luteinizing hormone releasing factor by the hypothalamus, these findings suggest a link between the neuroendocrine mechanisms that initiate such episodic secretion and those responsible for the onset of flush episodes. Copyright © 1979 AAAS.
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页码:823 / 825
页数:3
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