SYNTHESIS OF SUBSTITUTED 4 H-THIENO[2,3-B][1]BENZOTHIOPYRAN-4-ONES AS POSSIBLE SCHISTOSOMICIDAL AGENTS

被引：4
作者：
ELKERDAWY, MM
ELEMAM, AA
ELSUBBAGH, HI
ABUSHANAB, E
机构：
[1] UNIV MANSOURA,FAC PHARM,DEPT MED CHEM,MANSOURA,EGYPT
[2] UNIV RHODE ISL,COLL PHARM,DEPT MED CHEM,KINGSTON,RI 02881
来源：
MONATSHEFTE FUR CHEMIE | 1990年 / 121卷 / 01期
关键词：
4 H-Thieno[2,3-b][1]benzothiopyran-4-ones; Synthesis;
D O I：
10.1007/BF00810293
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new series of thiophenic isosters of thioxanthones, namely: 2-substituted-4 H-thieno[2,3-b][1]benzothiopyran-4-ones and 5-substituted-2-nitro-8-methyl-4 H-thieno[2,3-b][1]benzothiopyran-4-ones were synthesized as potential schistosomicidal agents. The synthesized compounds were characterized by their1H-NMR data. © 1990 Springer-Verlag.
引用
收藏
页码：45 / 50
页数：6
相关论文
共 50 条
  • [31] Synthesis and anticancer activity of [1,2,4] triazole [4,3-b] [1,2,4,5] tetrazine derivatives
    Pei, Tianyun
    Zhang, Xuanhe
    Yang, Zhenzhen
    Ke, Zhonglu
    Shi, Qingsong
    Mao, Qingqing
    Gong, Shunze
    Zeng, Hanwei
    Xu, Feng
    Xu, Defeng
    PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2022, 197 (08) : 819 - 824
  • [32] Synthesis of some new quinazoline-4-(3H)-ones and styryl hemicyanines as possible antimicrobial agents
    Afsah, SA
    Ahmad, J
    Purbey, R
    Kumar, A
    ASIAN JOURNAL OF CHEMISTRY, 2003, 15 (01) : 552 - 554
  • [33] Synthesis and pharmacological investigation of novel 1-alkyl-4-(4-substituted aryl/heteroaryl)-1,2,4-triazolo[4,3-a]quinazolin-5(4H)-ones as a new class of H1-antihistaminic agents
    Alagarsamy, Veerachamy
    Yadav, Mangae Ram
    Giridhar, Rajani
    ARZNEIMITTELFORSCHUNG-DRUG RESEARCH, 2006, 56 (12): : 834 - 841
  • [34] A new approach to the facile synthesis of 2-substituted-quinazolin-4(3H)-ones
    Wang, Bin
    Li, Zeng
    Wang, Xiao Ning
    Tan, Jia Heng
    Gu, Lian Quan
    Huang, Zhi Shu
    CHINESE CHEMICAL LETTERS, 2011, 22 (08) : 951 - 953
  • [35] Synthesis of 3-substituted pyrido[4′,3′: 4,5]thieno[2,3-d]pyrimidines and related fused thiazolo derivatives
    Ahmed, EK
    PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2003, 178 (04) : 667 - 679
  • [36] A new approach to the facile synthesis of 2-substituted-quinazolin-4(3H)-ones
    Bin Wang~(a
    Chinese Chemical Letters, 2011, 22 (08) : 951 - 953
  • [37] Targeted Synthesis and Study of Anti-tyrosinase Activity of 2-Substituted Tetrahydrobenzo[4,5]Thieno[2,3-d]Pyrimidine-4(3H)-One
    Chiriapkin, Alexey
    Kodonidi, Ivan
    Pozdnyakov, Dmitry
    IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH, 2022, 21 (01):
  • [38] SYNTHESIS OF 2,4,5-TRIARYL-5H-CHROMENO[4,3-b]PYRIDINES IN IONIC LIQUID
    Wu, Hui
    Wan, Yu
    Chen, Xiu-mei
    Lu, Lei-lei
    Shen, Yang
    Chen, Cai-fa
    Xin, Hai-qiang
    Xu, Hua-hong
    Pang, Li-ling
    Ma, Rui
    Yue, Cai-hui
    HETEROCYCLES, 2009, 78 (02) : 357 - 367
  • [39] Synthesis and evaluation of 7-substituted-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-ones as anticonvulsant and hypnotic agents
    Xian-Qing Deng
    Ming-Xia Song
    Cheng-Xi Wei
    Zhi-Gang Sun
    Zhe-Shan Quan
    Medicinal Chemistry Research, 2011, 20 : 996 - 1004
  • [40] Synthesis and evaluation of 7-substituted-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-ones as anticonvulsant and hypnotic agents
    Deng, Xian-Qing
    Song, Ming-Xia
    Wei, Cheng-Xi
    Sun, Zhi-Gang
    Quan, Zhe-Shan
    MEDICINAL CHEMISTRY RESEARCH, 2011, 20 (07) : 996 - 1004
12345