A NEW ALPHA-SELECTIVE SYNTHETIC EQUIVALENT FOR THE CROTYL ANION IN ADDITIONS TO IMINES

被引：19

作者：

BETZ, J ^{[1
]}

HEUSCHMANN, M ^{[1
]}

机构：

[1] UNIV MUNICH,INST ORGAN CHEM,D-80333 MUNICH,GERMANY

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 23期

关键词：

D O I：

10.1016/0040-4039(95)00670-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two equivalents of vinylmagnesium bromide add to imines 1 in the presence of cerium trichloride to form homoallylic amines 3 as 2:1-adducts, Z-diastereomers being preferred by a margin of 88:12 to 71:29. Suitable chiral imines 1g-i are transformed to l-products l-3g-i with high diastereoselectivity.

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页码：4043 / 4046

页数：4

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