MANAGEMENT OF INJURIES CAUSED BY CRYPTOCOCCUS NEOFORMANS-CONTAMINATED NEEDLES

被引：18
作者：
CASADEVALL, A
MUKHERJEE, J
YUAN, RR
PERFECT, J
机构：
[1] YESHIVA UNIV ALBERT EINSTEIN COLL MED,DEPT MICROBIOL & IMMUNOL,BRONX,NY 10461
[2] YESHIVA UNIV ALBERT EINSTEIN COLL MED,DEPT CELL BIOL,BRONX,NY 10461
[3] DUKE UNIV,DEPT MED,DURHAM,NC
来源：
CLINICAL INFECTIOUS DISEASES | 1994年 / 19卷 / 05期
关键词：
D O I：
10.1093/clinids/19.5.951
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
This report describes four skin-puncture accidents with needles that were heavily contaminated with Cryptococcus neoformans. In one accident, delayed administration of antifungal drugs resulted in a granuloma of the finger. In the other three accidents, no skin infection followed immediate prophylaxis with oral fluconazole. Our experience suggests that early therapy with fluconazole is a reasonable means of managing skin injuries caused by instruments contaminated with viable C. neoformans.
引用
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页码：951 / 953
页数：3
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