INDOMETHACIN TREATMENT IN OSTEOARTHRITIS OF THE HIP-JOINT - DOES THE TREATMENT INTERFERE WITH THE NATURAL COURSE OF THE DISEASE

被引：81
|
作者：
RONNINGEN, H [1 ]
LANGELAND, N [1 ]
机构：
[1] UNIV OSLO, SOPHIES MINDE ORTHOPAED HOSP, OSLO, NORWAY
来源：
ACTA ORTHOPAEDICA SCANDINAVICA | 1979年 / 50卷 / 02期
关键词：
Hip joint; Indomethacin; Osteoarthritis;
D O I：
10.3109/17453677908989752
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
The course of osteoarthritis in 294 hips of 186 patients was evaluated by examining their radiographs. the development of the disease in patients treated with indomethacin was compared with that in a control material. In the indomethacin group the disease progressed more frequently and in one parameter the progress was more severe. the results support previous reports indicating that indomethacin might have a deleterious effect on osteoarthritic hip joints. Some possible explanations for this adverse effect of indomethacin treatment are discussed. © 1979 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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页码：169 / 174
页数：6
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