Chordoid Meningioma - A Case Report: Clinicopathological Features and Differential Diagnosis of an Uncommon Tumor

被引:0
|
作者
Ozer, Hatice [1 ]
Tuncer, Ersin [1 ]
Saray, Gonul [1 ]
Gurelik, Mustafa [2 ]
Oztoprak, Ibrahim [3 ]
Egilmez, Reyhan [1 ]
机构
[1] Cumhuriyet Univ, Fac Med, Dept Pathol, Sivas, Turkey
[2] Cumhuriyet Univ, Fac Med, Dept Neurosurg, Sivas, Turkey
[3] Cumhuriyet Univ, Fac Med, Dept Radiol, Sivas, Turkey
关键词
Central nervous system neoplasms; Meningioma; Differential diagnosis;
D O I
10.5146/tjpath.2013.01209
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Meningiomas are tumors that originate from the arachnoid cell and the majority are benign and grade I tumors according to World Health Organization. Chordoid meningioma is an uncommon variant of meningioma and corresponds to grade II tumor in the World Health Organization Classification of Tumors of the Nervous System 2007 because of its more aggressive behavior and increased likelihood of recurrence. A 75-year-old female was referred to the neurosurgery department complaining of headache, syncope, and seizure. Radiological examination revealed a mass lesion in the neighbourhood of the frontal lobe that destructed bone and was associated with peritumoral edema. The patient underwent surgery. The tumor was totally excised with the dura beneath. Histopathological examination showed that the tumor was composed of clusters and cords of small polygonal cells with fine chromatin and eosinophilic vacuolated cytoplasm embedded in a myxoid matrix, and also focal whorls of spindle-shaped cells. Two mitoses were seen in 10 high power fields. Vascular proliferation was observed in some tumoral areas. Bone invasion was present. Immunohistochemical analysis of the tumor cells revealed widespread strong membranous and cytoplasmic expression of epithelial membrane antigen. The Ki67 labeling index was 6-8%. All of these findings were consistent with a diagnosis of chordoid meningioma, the neoplasm was identified as grade II based on the World Health Organization Classification, 2007. In this report we present a case of chordoid meningioma without classical radiological findings of meningioma with areas of vascular proliferation that mimicked glial tumors at histopathologic examination.
引用
收藏
页码:130 / 134
页数:5
相关论文
共 50 条
  • [21] Intraparenchymal cystic chordoid meningioma: A case report and review of the literature
    Zhao, Song-li
    Li, Yang
    Tian, Xiao-ying
    Li, Zhi
    Huang, Quan
    Li, Bin
    NEUROPATHOLOGY, 2011, 31 (06) : 648 - 653
  • [22] Spinal chordoid meningioma in a child: A case report and review of the literature
    Wu, Liang
    Yang, Tao
    Fang, Jingyi
    Zhang, Junting
    Xu, Yulun
    ONCOLOGY LETTERS, 2015, 10 (06) : 3727 - 3731
  • [23] A case report of chordoid glioma with unusual features: Immunohistochemical and molecular findings and differential diagnoses
    Tauziede-Espariat, Arnault
    Robert, Gilles
    de Cremoux, Patricia
    Polivka, Marc
    ANNALES DE PATHOLOGIE, 2017, 37 (02) : 151 - 157
  • [24] Chordoid meningioma of the foramen magnum in a child: a case report and review of the literature
    Alfonso Marhx-Bracho
    Fernando Rueda-Franco
    Abraham Ibarra-de la Torre
    Oscar García-González
    Leticia Bornstein-Quevedo
    Beatriz de León-Bogorge
    Child's Nervous System, 2008, 24 : 623 - 627
  • [25] A thoracic extradural chordoid meningioma: a unique case report and literature review
    Tulloch, Isabel
    Georges, Husam
    Phadke, Rahul
    Hardwidge, Carl
    BRITISH JOURNAL OF NEUROSURGERY, 2020, 34 (01) : 112 - 114
  • [26] Cytopathologic Features of Orbital Intraosseous Chordoid Meningioma: Report of a Case and Distinction From Other Myxoid/Mucoid Tumors
    Hayashi, Toshitetsu
    Haba, Reiji
    Kushida, Yoshio
    Kadota, Kyuichi
    Katsuki, Naomi
    Bando, Kenji
    Miyai, Yumi
    Shibuya, Shinsuke
    Funamoto, Yasunobu
    Shindo, Atsushi
    Miyake, Keisuke
    Tamiya, Takashi
    DIAGNOSTIC CYTOPATHOLOGY, 2010, 38 (11) : 818 - 821
  • [28] CYTOPATHOLOGIC FEATURES OF ORBITAL INTRAOSSEOUS CHORDOID MENINGIOMA: REPORT OF A CASE AND DISTINCTION FROM OTHER MYXOID/MUCOID TUMORS
    Hayashi, T.
    Haba, R.
    Kushida, Y.
    Shibuya, S.
    ACTA CYTOLOGICA, 2010, 54 (03) : 520 - 520
  • [29] Chordoid meningioma of the foramen magnum in a child:: a case report and review of the literature
    Marhx-Bracho, Alfonso
    Rueda-Franco, Fernando
    la Torre, Abraham Ibarra-de
    Garcia-Gonzalez, Oscar
    Bornstein-Quevedo, Leticia
    De Leon-Bogorge, Beatriz
    CHILDS NERVOUS SYSTEM, 2008, 24 (05) : 623 - 627
  • [30] Extra-axial chordoid meningioma: case report and literature review
    Skounti, Khalid
    Mounadi, Mohamed
    Mortada, Jihed
    PAN AFRICAN MEDICAL JOURNAL, 2023, 44 : 174