EFFECTS OF ANTIOXIDANT THERAPY ON PERFUSION AND CONTRACTILITY OF LEFT-VENTRICULAR MYOCARDIUM IN PATIENTS WITH ALCOHOLIC INJURY OF THE HEART

被引：0
|
作者：
ESCHANOVA, FS
GORGASLIDZE, AG
SMETNEV, AS
SERGIENKO, VB
机构：
来源：
KARDIOLOGIYA | 1994年 / 34卷 / 1-2期
关键词：
ALCOHOLIC MYOCARDIAL INJURY; ALCOHOLIC CARDIOMYOPATHY; ANTIOXIDANTS; ANTIOXIDANT THERAPY; MYOCARDIAL PERFUSION; MYOCARDIAL FUNCTION;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Antioxidant Dibunol (20 mg/kg daily) was given for 20 days to 30 patients with alcoholic injury of the heart. Ten patients served as controls and received placebo for 20 days. Myocardial scintigraphy with thallium 201 and radionuclide equilibrium ventriculography at rest and during stress test were performed before and after Dibunol or placebo. Relative to baseline values Dibunol treated patients had increased left ventricular ejection fraction, maximal filling and ejection velocities, decreased enddiastolic and endsystolic volumes, increased myocardial TI 201 uptake and improved TI 201 washout. Therapy with Dibunol resulted in improvement of left ventricular perfusion and function.
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页码：39 / 42
页数：4
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