4H-PYRROLO[1,2-A]THIENO[3,2-F] AND 4H-PYRROLO[1,2-A]THIENO[2,3-F][1,4]DIAZEPINES - SYNTHESIS AND PHARMACOLOGICAL EVALUATION

被引:5
|
作者
VEGA, S [1 ]
GIL, MS [1 ]
DARIAS, V [1 ]
MATEO, CCS [1 ]
EXPOSITO, MA [1 ]
TELLO, ML [1 ]
ALBERTOS, LM [1 ]
机构
[1] UNIV LA LAGUNA,FAC FARM,DEPT FARMACOL,TENERIFE,SPAIN
关键词
D O I
10.1002/ardp.19943271108
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
As an extension of a previous work, in which a number of 4H-pyrrolo-[1,2-a]thieno[2,3-f][1,4]diazepines were described a new series of derivatives of the isomeric pyrrolo[1,2-a]thieno[3,2-f]diazepines ring system has been synthesized. The products obtained, together with those reported in the previous paper, were rested for acute toxicity and CNS activity in mice.
引用
收藏
页码:721 / 728
页数:8
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