METABOLISM OF ANTIHYPERTENSIVE AGENT 1,4-DIHYDRO-2,6-DIMETHYL-4-(2-TRIFLUOROMETHYLPHENYL)-3,5-PYRIDINEDICARBOXYLIC ACID DIETHYL ESTER

被引：29
|
作者：
WALKENSTEIN, SS [1 ]
INTOCCIA, AP [1 ]
FLANAGAN, TL [1 ]
HWANG, B [1 ]
FLINT, D [1 ]
WEINSTOCK, J [1 ]
VILLANI, AJ [1 ]
BLACKBURN, D [1 ]
GREEN, H [1 ]
机构：
[1] SK&F LABS, RES & DEV DIV, PHILADELPHIA, PA 19101 USA
来源：
JOURNAL OF PHARMACEUTICAL SCIENCES | 1973年 / 62卷 / 04期
关键词：
D O I：
10.1002/jps.2600620407
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：580 / 584
页数：5
相关论文
共 50 条
  • [41] Diethyl 2,6-dimethyl-4-[5-(4-methyl-phenyl)-1H-pyrazol-4-yl]-1,4-dihydro-pyridine-3,5-dicarboxylate
    Islor, Arun M.
    Malladi, Shridhar
    Telkar, Sandeep
    Gerber, Thomas
    Hosten, Eric
    Betz, Richard
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O3269 - +
  • [42] Synthesis and X-ray crystal structure of the calcium channel antagonist:: dimethyl 1,4-dihydro-2,6-dimethyl-4-[4′-(4H-4-oxo-1-benzopyran-2-yl)phenyl]-3,5-pyridine dicarboxylate
    Tunçbilek, M
    Özbey, S
    Kendi, E
    Yildirim, E
    Erol, K
    Ertan, R
    FARMACO, 1999, 54 (10): : 660 - 665
  • [43] SYNTHESIS AND SELECTIVE VASODILATING PROPERTIES OF ESTERS OF 2,6-DIMETHYL-4-(2-DIFLUOROMETHOXYPHENYL)-1,4-DIHYDRO-PYRIDINE-3,5-DICARBOXYLIC ACID
    DUBUR, GJ
    VEVERIS, MM
    WEINHEIMER, G
    BISENIEKS, EA
    MAKAROVA, NR
    KIMENIS, AA
    ULDRIKIS, JR
    LUKEVICS, EJ
    DOOLEY, D
    OSSWALD, H
    ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, 1989, 39-2 (10): : 1185 - 1189
  • [44] Diethyl 2,6-dimethyl-4-[5-(4-nitrophenyl)-2-furyl]-1,4-dihydropyridine-3,5-dicarboxylate
    Vrábel, V
    Fronc, M
    Svoboda, I
    Marchalín, T
    Baumlová, B
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2005, 61 : O3592 - O3594
  • [45] Diethyl 2,6-dimethyl-4-(5-phenyl-1H-pyrazol-4-yl)-1,4-dihydropyridine-3,5-dicarboxylate
    Fun, Hoong-Kun
    Ooi, Chin Wei
    Malladi, Shridhar
    Shivananda, K. N.
    Isloor, Arun M.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O892 - U3336
  • [46] SOLVENT-FREE SYNTHESIS OF DIETHYL-1,4-DIHYDRO-2,6-DIMETHYL-4-(1,3-DIARYL-1H-PYRAZOLE-4-YL)/CYCLOALKYL PYRIDINE-3,5-DICARBOXYLATES AS POTENT ANTIMICROBIAL AGENTS
    Ashok, D.
    Shravani, D.
    Sarasija, M.
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2012, 21 (03) : 233 - 236
  • [47] POLYMORPHISM OF METHYL (E)-3-PHENYL-2-PROPEN-1-YL 1,4-DIHYDRO-2,6-DIMETHYL-4-(3-NITROPHENYL)PYRIDINE-3,5-DICARBOXYLATE (FRC-8411)
    WATANABE, D
    FUKUTANI, T
    IKAWA, H
    YAMAURA, T
    KASE, N
    MIZUTANI, H
    CHEMICAL & PHARMACEUTICAL BULLETIN, 1986, 34 (11) : 4855 - 4858
  • [48] Synthesis and evaluation of pharmacological activities of 3,5-dialkyl 1,4-dihydro-2,6-dimethyl-4-nitroimidazole-3,5-pyridine dicarboxylates
    Miri, R
    Javidnia, K
    Kebriaie-Zadeh, A
    Niknahad, H
    Shaygani, N
    Semnanian, S
    Shafiee, A
    ARCHIV DER PHARMAZIE, 2003, 336 (09) : 422 - 428
  • [49] Synthesis and calcium channel antagonist activities of new derivatives of dialkyl 1,4-dihydro-2,6-dimethyl-4-(5-phenylisoxazol-3-yl)pyridine-3,5-dicarboxylates
    N. Daryabari
    T. Akbarzadeh
    M. Amini
    R. Miri
    H. Mirkhani
    A. Shafiee
    Journal of the Iranian Chemical Society, 2007, 4 : 30 - 36
  • [50] Dimethyl 1,4-Dihydro-2,6-dimethyl-1-(4-methylphenyl)-4-(4-methoxylphenyl) pyridine-3,5-dicarboxylate
    Zhang, Wenwen
    Pan, Ning
    Liu, Qingjian
    MOLBANK, 2009, (04)
12345