TRANSITION-STATE STABILIZATION AND MOLECULAR RECOGNITION - ACCELERATION OF PHOSPHORYL-TRANSFER REACTIONS BY AN ARTIFICIAL RECEPTOR

被引：62

作者：

TECILLA, P ^{[1
]}

CHANG, SK ^{[1
]}

HAMILTON, AD ^{[1
]}

机构：

[1] UNIV PITTSBURGH, DEPT CHEM, PITTSBURGH, PA 15260 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1990年 / 112卷 / 26期

关键词：

D O I：

10.1021/ja00182a017

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An artificial receptor that is complementary to the proposed trigonal-bipyramidal intermediate for phosphoryl-transfer reactions has been designed. Kinetic measurements with P-31 NMR methods show that the receptor causes up to a 10-fold accleration in the aminolysis of phosphorodiamidic chloride derivatives, proceeding via an associative mechanism.

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收藏

页码：9586 / 9590

页数：5

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