CONCERTED EVOLUTION OF DUPLICATED PROTEIN-CODING GENES IN DROSOPHILA

被引：47
作者：
HICKEY, DA
BALLYCUIF, L
ABUKASHAWA, S
PAYANT, V
BENKEL, BF
机构：
[1] Department of Biology, University of Ottawa, Ottawa
来源：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1991年 / 88卷 / 05期
关键词：
GENE CONVERSION; GENE DUPLICATION; MOLECULAR EVOLUTION; ALPHA-AMYLASE;
D O I：
10.1073/pnas.88.5.1611
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Very rapid rates of gene conversion were observed between duplicated alpha-amylase-coding sequences in Drosophila melanogaster. This gene conversion process was also seen in the related species Drosophila erecta. Specifically, there is virtual sequence identity between the coding regions of the two genes within each species, while the sequence divergence between species is close to that expected based on their phylogenetic relationship. The flanking, noncoding regions are much more highly diverged and do not appear to be subject to gene conversion. Comparison of amylase sequences between the two species provides a clear demonstration that recurrent gene conversion does indeed lead to the concerted evolution of the gene pair.
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页码：1611 / 1615
页数：5
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